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Fig. 1 | Advances in Rheumatology

Fig. 1

From: PLCL1 regulates fibroblast-like synoviocytes inflammation via NLRP3 inflammasomes in rheumatoid arthritis

Fig. 1

The expression of PLCL1 was up-regulated in the K/BxN mice and RA FLS. a The mRNA level of IL12RB2, PLCL1, CCR2, TCF7 and IQGAP1 was analyzed by RT-QPCR in OA and RA synovial tissue. b Typical H&E staining of synovial tissues and their pathology scores in KRN mice and the K/BxN mice (original magnification, × 20). c The expression of PLCL1 in synovial tissue of the KRN mice and the K/BxN mice was analyzed by IHC staining. d Typical H&E staining of OA and RA synovial tissues (original magnification, × 20). e The level of PLCL1 protein in OA and RA synovial tissue was analyzed by IHC staining in human. f The level of PLCL1 protein in OA and RA synovial tissue was detected by WB. (Compared with the control group # P < 0.05, ## P < 0.01.)

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Advances in Rheumatology

ISSN: 2523-3106