Table 3 Demographic data, clinical characteristics, tuberculosis screening tests, and treatment for tuberculosis in Portuguese and Brazilian juvenile idiopathic arthritis populations undergoing the test at disease onset or prior to the use of conventional and biologic Disease Modified Anti-Rheumatic Drugs (DMARDs)
Test performed at JIA onset | Test performed before starting cDMARD | Test performed before starting bDMARD | p value | |
|---|---|---|---|---|
Number of patients (%) | 118 (42) | 76 (27) | 87 (31) | – |
Current age (mean ± SD) (years) | 12.1 ± 6.5 | 15.4 ± 6.3 | 16.3 ± 6.8 | < 0.001 |
Disease duration (mean ± SD) (years) | 5.6 ± 5.0 | 7.7 ± 5.7 | 9.7 ± 7.4 | < 0.001 |
Female (%) | 73 (61.9) | 44 (57.9) | 56 (64.4) | 0.696 |
TST performed (%) | 114 (96.6) | 67 (88.2) | 87 (100) | 0.001 |
TST ≥ 5 mm (%) | 13 (11.4) | 9 (13.4) | 5 (5.7) | 0.240 |
Chest X-ray performed (%) | 65 (55.1) | 61 (80.3) | 72 (82.8) | < 0.001 |
Abnormal chest X-ray (%) | 6 (9.2) | 0 | 2 (2.8) | 0.064 |
IGRA performed (%)*1 | 17 (14.4) | 39 (51.3) | 38 (43.7) | < 0.001 |
IGRA positive (%) | 0 | 3 (7.9) | 0 | 0.106 |
LTBI therapy (isoniazid) (%) | 12 (10.2) | 11 (14.5) | 5 (5.7) | 0.178 |
Tuberculosis therapy (%) | 3 (2.5) | 0 | 0 | 0.123 |