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Table 4 Disease-modifying antirheumatic or immunossupressive drugs used by patients with rheumatoid arthritis at the time of the study

From: Factors associated with hospitalizations for Covid-19 in patients with rheumatoid arthritis: data from the Reumacov Brazil registry

Hospitalization

No

Yes

P

N = 215

N = 54

Disease-modifying antirheumatic or immussupressive drugs

   

Without treatment

  

1.000a

 No n (%)

210/215 (97.7)

53/54 (98.1)

 

 Yes n (%)

5/215 (2.3)

1/54 (1.9)

 

Abatacept

  

0.202a

 No n (%)

210/215 (97.7)

51/54 (94.4)

 

 Yes n (%)

5/215 (2.3)

3/54 (5.6)

 

IL-17 inhibitors?

  

–

 No n (%)

215/215 (100.0)

54/54 (100.0)

 

IL12/23 inhibitors?

  

1.000a

 No n (%)

214/215 (99.5)

54/54 (100.0)

 

 Yes n (%)

1/215 (0.5)

0/54 (0.0)

 

TNF inhibitors

  

0.014

 No n (%)

147/215 (68.4)

46/54 (85.2)

 

 Yes n (%)

68/215 (31.6)

8/54 (14.8)

 

Azathioprine

  

0.040a

 No n (%)

215/215 (100.0)

52/54 (96.3)

 

 Yes n (%)

0/215 (0.0)

2/54 (3.7)

 

Belimumab?

  

–

 No n (%)

215/215 (100.0)

54/54 (100.0)

 

Cyclophosphamide oral

  

–

 No n (%)

215/215 (100.0)

54/54 (100.0)

 

Ciclosporin

  

–

 No n (%)

215/215 (100.0)

54/54 (100.0)

 

Corticosteroids (oral)

  

0.004a

 No use

149/215 (69.3)

26/54 (48.1)

 

 < 10 mg/day n (%)

58/215 (27.0)

20/54 (37.0)

 

 ≥ 11 to 20 mg/day n (%)

6/215 (2.8)

7/54 (13.0)

 

 ≥ 21 mg/day n (%)

2/215 (0.9)

1/54 (1.9)

 

Hydroxychloroquine

  

0.910

 No n (%)

194/215 (90.2)

49/54 (90.7)

 

 Yes n (%)

21/215 (9.8)

5/54 (9.3)

 

JAKi

  

0.789a

 No n (%)

197/215 (91.6)

49/54 (90.7)

 

 Yes n (%)

18/215 (8.4)

5/54 (9.3)

 

Leflunomide

  

0.791

 No n (%)

163/215 (75.8)

40/54 (74.1)

 

 Yes n (%)

52/215 (24.2)

14/54 (25.9)

 

Methotrexate

  

0.783

 No use n (%)

117/211 (55.5)

32/54 (59.3)

 

 ≤ 20 mg/week n (%)

77/211 (36.5)

17/54 (31.5)

 

 ≥ 21 mg/week n (%)

17/211 (8.1)

5/54 (9.3)

 

Mycophenolatemofetil

  

–

 No n (%)

215/215 (100.0)

54/54 (100.0)

 

Cyclophosphamide pulsotherapy

  

–

 No n (%)

215/215 (100.0)

54/54 (100.0)

 

Methylprednisolone (pulsotherapy)

  

–

 No n (%)

215/215 (100.0)

54/54 (100.0)

 

Rituximab

  

0.490a

 No n (%)

205/215 (95.3)

50/54 (92.6)

 

 Yes n (%)

10/215 (4.7)

4/54 (7.4)

 

Sulfasalazine

  

0.346a

 No n (%)

211/215 (98.1)

52/54 (96.3)

 

 Yes n (%)

4/215 (1.9)

2/54 (3.7)

 

Tocilizumab

  

0.687

 No n (%)

191/215 (88.8)

49/54 (90.7)

 

 Yes n (%)

24/215 (11.2)

5/54 (9.3)

 

Others

  

0.283

 No n (%)

183/215 (85.1)

49/54 (90.7)

 

 Yes n (%)

32/215 (14.9)

5/54 (9.3)

 

scDMARD

  

0.878

 No n (%)

62/215 (28.8)

15/54 (27.8)

 

 Yes n (%)

153/215 (71.2)

39/54 (72.2)

 

bDMARD

  

0.083

 No n (%)

107/215 (49.8)

34/54 (63.0)

 

 Yes n (%)

108/215 (50.2)

20/54 (37.0)

 

Withdrawal

  

0.010

 No n (%)

168/215 (78.1)

33/54 (61.1)

 

 Yes n (%)

47/215 (21.9)

21/54 (38.9)

 
  1. P—Chi-Square test, Fisher's exact (a) or Student's t