Table 2 Clinical features and test results suggestive of latent tuberculosis infection in patients with chronic inflammatory arthritis after exposure to TNFα inhibitors
LTBI parameters | JIA (n = 20) | RA (n = 40) | AS (n = 35) | PsA (n = 7) | p value |
|---|---|---|---|---|---|
BCG scar | 20 (100%) | 19 (47.5%) | 27 (77.1%) | 5 (71.4%) | 0.001 |
Chest X-ray abnormalities | 0 | 2 (5%) | 1 (2.8%) | 0 | 0.834 |
Positive TB epidemiology | 0 | 7 (17.5%) | 4 (11.4%) | 1 (14.3%) | 0.214 |
Positive TST | 0 | 12 (30%) | 13 (37.1%) | 3 (42.9%) | 0.017 |
Positive IGRA | |||||
T-SPOT.TB | 1 (5%) | 14 (35%) | 10 (28.6%) | 2 (28.6%) | 0.097 |
Quantiferon | 1 (5%) | 9 (22.5%) | 7 (20%) | 2 (28.6%) | 0.277 |