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Table 4 Multivariable analyses of association between clinical factors and depression in rheumatoid arthritis patients (N = 507)

From: Factors associated with anxiety and depression in rheumatoid arthritis patients: a cross-sectional study

 

Univariable analysis

Multivariable analysis

Model 1

Model 2

Odds ratio (95% CI)

p value

Odds ratio (95% CI)

p value

Odds ratio (95% CI)

p value

Sex

0.80 (0.49, 1.34)

0.39

0.70 (0.40, 1.22)

0.21

0.61 (0.34, 1.07)

0.09

Age (10 years)

1.18 (1.01, 1.38)

0.04

1.03 (0.87, 1.24)

0.70

1.04 (0.87, 1.24)

0.68

DAS28-CRP-based non-remission

2.37 (1.47, 3.82)

 < 0.01

1.45 (0.81, 2.61)

0.22

  

TJC

1.10 (0.97, 1.25)

0.14

  

0.96 (0.81, 1.14)

0.63

SJC

1.06 (0.92, 1.21)

0.40

  

0.94 (0.78, 1.14)

0.55

CRP

1.01 (0.74, 0.99)

0.96

  

0.71 (0.50, 1.01)

0.06

PtGA (0–10)

1.27 (1.17, 1.38)

 < 0.01

  

1.21 (1.09, 1.35)

 < 0.01

HAQ-DI non-remission

2.96 (1.96, 4.53)

 < 0.01

2.65 (1.56, 4.50)

 < 0.01

1.95 (1.15, 3.31)

0.01

Pain VAS (0–10)

1.13 (1.05, 1.22)

 < 0.01

0.98 (0.88, 1.09)

0.77

  

Biological DMARDs

0.92 (0.61, 1.37)

0.68

0.84 (0.53, 1.33)

0.45

0.88 (0.55, 1.40)

0.58

Methotrexate

0.60 (0.40, 0.90)

0.01

0.72 (0.45, 1.14)

0.16

0.76 (0.48, 1.22)

0.26

Steroid

1.87 (1.24, 2.81)

 < 0.01

1.48 (0.93, 2.34)

0.09

1.66 (1.03, 2.67)

0.04

  1. Model adjusted for age (stratified in 10 decades), pain (VAS), HAQ-DI-based remission, and treatment type. DAS28 score was used to gauge clinical remission (score < 2.6). DAS4 variables comprise TJC, SJC, CRP, and PtGA. VAS range: 0 (no pain) to 10 (maximum pain)
  2. CI confidence interval, DAS28 Disease Activity Score in 28 joints, CRP C-reactive protein, TJC tender joint count, SJC swollen joint count, PtGA patient global assessment, HAQ-DI Health Assessment Questionnaire Disability Index, VAS Visual Analogue Scale, DMARDs biological disease-modifying anti-rheumatic drugs