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Table 1 Epidemiological and clinical data between patients with rheumatic diseases and household contacts at baseline

From: Chronic use of hydroxychloroquine did not protect against COVID-19 in a large cohort of patients with rheumatic diseases in Brazil

Variables

All

RD patients

Household co-habitants

Difference (CI 95%)

p*

N = 9589

N = 5166

N = 4423

n (%)

n (%)

n (%)

Age, years (SD)

43.5 (14.9)

43.1 (13.9)

44.0 (16.1)

0.90 (0.29; 1.50)

0.039

Sex

     

Women

6617 (69.4)

4772 (92.6)

1845 (42.2)

50.4 (48.8; 52.0)

 < 0.001

Men

2912 (30.6)

382 (7.4)

2530 (57.8)

  

Schooling

     

Basic or illiterate

2522 (26.5)

1296 (25.1)

1226 (28)

2.9 (1.1; 4.7)

 < 0.001

High school

4027 (42.2)

2166 (42)

1861 (42.6)

0.6 (− 1.39; 2.6)

 

College

2983 (31.3)

1697 (32.9)

1286 (29.4)

3.5 (1.6; 5.4)

 

Profession

     

Customer assistance

1911 (20.2)

946 (18.5)

965 (22.2)

3.7 (2.1; 5.3)

 < 0.001

Healthcare

683 (7.2)

443 (8.7)

240 (5.5)

3.2 (2.2; 4.2)

 

Safety professionals

182 (1.9)

43 (0.8)

139 (3.2)

2.4 (1.8; 3.0)

 

Education

636 (6.7)

438 (8.6)

198 (4.6)

4.0 (3.0; 4.9)

 

Housewife

1662 (17.6)

1236 (24.2)

426 (9.8)

14.4 (12.9; 15.9)

 

Others

4382 (46.3)

2011 (39.3)

2371 (54.6)

15.3 (13.3; 17.3)

 

Contact with confirmed case of COVID-19

     

No

8136 (85.3)

4484 (86.9)

3652 (83.4)

3.5 (2.1; 4.9)

 < 0.001

Yes

727 (7.6)

380 (7.4)

347 (7.9)

0.5 (− 0.6; 1.6)

 

Unknown

673 (7.1)

294 (5.7)

379 (8.7)

3.0 (1.9; 4.1)

 

Family unit in social distancing

5787 (60.7)

3235 (62.7)

2552 (58.4)

4.3 (2.3; 6.3)

 < 0.001

Heart disease

496 (5.3)

314 (6.2)

182 (4.3)

1.9 (1.0; 2.8)

 < 0.001

Diabetes

703 (7.5)

339 (6.7)

364 (8.5)

1.8 (0.7; 2.9)

 < 0.001

Lung disease

497 (5.3)

357 (7)

140 (3.3)

3.7 (2.8; 4;6)

 < 0.001

Kidney disease

602 (6.4)

565 (11.1)

37 (0.9)

10.2 (9.3; 11.1)

 < 0.001

Hypertension

2673 (28.6)

1692 (33.3)

981 (23)

10.3 (8.5; 12.1)

 < 0.001

Influenza vaccine within last 30 days

2584 (27.2)

1527 (29.6)

1057 (24.2)

5.4 (3.6; 7.2)

 < 0.001

  1. Bold values indicate statistical significance (p < 0.05)
  2. The results are expressed as means, standard deviation and percentages
  3. CI, confidence interval; RD, rheumatic diseases; COVID-19, Coronavirus disease 2019
  4. *Chi-square test