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Table 3 Meta-analysis of the association between the TNFSF4 polymorphisms and SLE

From: Association of TNFSF4 polymorphisms with systemic lupus erythematosus: a meta-analysis

Population No. of studies Test of association Test of heterogeneity
OR 95% CI P I2 P model
rs844648 (A allele)        
Overall 5 1.11 [0.86, 1.43] 0.41 0.87  < 0.00001 Random
European 3 1.18 [0.88, 1.57] 0.26 0.82 0.004 Random
Latin American 1 0.73 [0.58, 0.91] 0.005 - - -
Asian 1 1.38 [1.15, 1.66]  < 0.001
rs2205960 (T allele)        
Overall 10 1.42 [1.36, 1.49]  < 0.00001 0 0.79 Fixed
African-American 2 1.45 [1.30, 1.62]  < 0.001 0 0.93 Fixed
Asian 8 1.42 [1.35, 1.49]  < 0.001 0 0.57 Fixed
rs844644 (A allele)        
Overall 5 0.92 [0.70, 1.21] 0.54 0.89  < 0.00001 Random
Asian 1 1.41 [1.18, 1.70]  < 0.001
European 3 0.87 [0.66, 1.15] 0.34 0.81 0.005 Random
Latin American 1 0.69 [0.55, 0.87] 0.001
rs10489265 (G allele)        
Overall 2 1.17 [0.94, 1.47] 0.17 0.87 0.006 Random
Asian 1 1.33 [1.14, 1.55]  < 0.001
European 1 1.06 [0.99, 1.12] 0.11
rs1234315 (T allele)        
Overall 5 1.41 [1.36, 1.46]  < 0.00001 0.68 0.01 Random
Asian 5 1.41 [1.36, 1.46]  < 0.00001 0.68 0.01 Random
rs704840 (G allele)        
Overall 5 1.34 [1.26, 1.42]  < 0.00001 0 0.43 Fixed
Asian 5 1.34 [1.26, 1.42]  < 0.00001 0 0.43 Fixed