Association of TNFSF4 polymorphisms with systemic lupus erythematosus: a meta-analysis

Table 3 Meta-analysis of the association between the TNFSF4 polymorphisms and SLE

Population	No. of studies	Test of association			Test of heterogeneity
Population	No. of studies	OR	95% CI	P	I²	P	model
rs844648 (A allele)
Overall	5	1.11	[0.86, 1.43]	0.41	0.87	< 0.00001	Random
European	3	1.18	[0.88, 1.57]	0.26	0.82	0.004	Random
Latin American	1	0.73	[0.58, 0.91]	0.005	-	-	-
Asian	1	1.38	[1.15, 1.66]	< 0.001	–	–	–
rs2205960 (T allele)
Overall	10	1.42	[1.36, 1.49]	< 0.00001	0	0.79	Fixed
African-American	2	1.45	[1.30, 1.62]	< 0.001	0	0.93	Fixed
Asian	8	1.42	[1.35, 1.49]	< 0.001	0	0.57	Fixed
rs844644 (A allele)
Overall	5	0.92	[0.70, 1.21]	0.54	0.89	< 0.00001	Random
Asian	1	1.41	[1.18, 1.70]	< 0.001	–	–	–
European	3	0.87	[0.66, 1.15]	0.34	0.81	0.005	Random
Latin American	1	0.69	[0.55, 0.87]	0.001	–	–	–
rs10489265 (G allele)
Overall	2	1.17	[0.94, 1.47]	0.17	0.87	0.006	Random
Asian	1	1.33	[1.14, 1.55]	< 0.001	–	–	–
European	1	1.06	[0.99, 1.12]	0.11	–	–	–
rs1234315 (T allele)
Overall	5	1.41	[1.36, 1.46]	< 0.00001	0.68	0.01	Random
Asian	5	1.41	[1.36, 1.46]	< 0.00001	0.68	0.01	Random
rs704840 (G allele)
Overall	5	1.34	[1.26, 1.42]	< 0.00001	0	0.43	Fixed
Asian	5	1.34	[1.26, 1.42]	< 0.00001	0	0.43	Fixed

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