Table 2 Characteristics of the individual studies included in meta-analysis
From: Association of TNFSF4 polymorphisms with systemic lupus erythematosus: a meta-analysis
Reference | Country | Ethnicity | Numbers | MAF | OR (95%) | P value | ||
|---|---|---|---|---|---|---|---|---|
Case | Control | Case | Control | |||||
rs1234315 (T allele) | ||||||||
Han et al. [17] | China | Asian | 4,199 | 8,255 | 0.503 | 0.421 | 1.37 (1.29–1.45) | 2.3 × 10–26 |
Zhang et al. [14] | China | Asian | 1,344 | 4,315 | 0.512 | 0.395 | 1.45 (1.34–1.60) | 1.5 × 10–16 |
Yang et al. [18] | China | Asian | 3,300 | 4,200 | 0.539 | 0.468 | 1.33 | 1.0 × 10–3 |
Xu et al. [1] | China | Asian | 294 | 282 | 0.531 | 0.434 | 1.47 (1.17–1.86) | 0.001 |
Chang et al. [19] | China | Asian | 314 | 920 | 0.538 | 0.445 | 1.46 (1.21–1.75) | 4. 9 × 10–5 |
rs844648 (A allele) | ||||||||
Delgado Vega et al. [20] | Germany | European | 259 | 322 | 0.470 | 0.400 | 1.29 (1.02–1.63) | 3.3 × 10–2 |
Delgado Vega et al. [20] | Italy | European | 258 | 223 | 0.430 | 0.350 | 1.40 (1.08–1.82) | 1.1 × 10–2 |
Delgado Vega et al. [20] | Spain, | European | 517 | 901 | 0.420 | 0.440 | 0.94 (0.80–1.10) | 0.407 |
Delgado Vega et al. [20] | Argentina | Latin American | 278 | 355 | 0.440 | 0.520 | 0.73 (0.58–0.91) | 3.9 × 10–3 |
Chang et al. [19] | Chinese | Asian | 314 | 920 | 0.546 | 0.465 | 1.39 (1.16–1.66) | 4.2 × 10–4 |
rs2205960 (T allele) | ||||||||
V Gupta et al. [21] | India | Asian | 394 | 583 | 0.277 | 0.225 | 1.32 (1.07–1.63) | < 0.01 |
Zhou et al. [13] | China | Asian | 722 | 804 | 0.345 | 0.274 | 1.39 (1.19–1.62) | 2.8 × 10–5 |
Sanchez et al. [22] | USA | African-American | 767 | 640 | 0.370 | 0.289 | 1.49 (1.27–1.75) | 1.7 × 10–6 |
Sanchez et al. [23] | USA | African-American | 2839 | 3441 | 0.070 | 0.049 | 1.44 (1.17–1.76) | 5.6 × 10–4 |
Han et al. [17] | China | Asian | 4,199 | 8,255 | 0.347 | 0.268 | 1.46 (1.37–1.56) | 2.5 × 10–32 |
Gupta et al. [21] | Indian | Asian | 394 | 583 | 0.225 | 0.277 | 1.32 (1.07–1.63) | < 0.01 |
Chua et al. [8] | Chinese | Asian | 198 | 178 | 0.298 | 0.248 | 1.27 (1.00–1.61) | 0.05 |
Chua et al. [8] | Malay | Asian | 42 | 43 | 0.193 | 0.189 | 1.03 (0.64–1.65) | 0.91 |
Chua et al. [8] | Indian | Asian | 24 | 12 | 0.387 | 0.167 | 3.16 (1.41–7.05) | 0.004 |
Chang et al. [19] | Chinese | Asian | 314 | 920 | 0.331 | 0.227 | 1.69 (1.39–2.06) | 1.95 × 10–7 |
rs704840 (G allele) | ||||||||
Chua et al. [8] | Chinese | Asian | 303 | 283 | 0.451 | 0.394 | 12.6 (1.02–1.56) | 0.03 |
Chua et al. [8] | Malay | Asian | 77 | 82 | 0.353 | 0.360 | 0.97 (0.67–1.44) | 0.89 |
Chua et al. [8] | Indian | Asian | 23 | 22 | 0.371 | 0.306 | 1.34 (0.65–2.75) | 0.42 |
Chang et al. [19] | Chinese | Asian | 314 | 920 | 0.490 | 0.390 | 1.51 (1.25–1.81) | 1.06 × 10–5 |
Yang et al. [18] | China | Asian | 3,300 | 4,200 | 0.491 | 0.420 | 1.33 | 1.21 × 10–3 |
rs844644 (A allele) | ||||||||
Chang et al. [19] | Chinese | Asian | 314 | 920 | 0.545 | 0.458 | 1.41 (1.18–1.70) | 1.82 × 10–4 |
Delgado Vega et al. [20] | Germany | European | 259 | 322 | 0.440 | 0.450 | 0.97 (0.76–1.22) | 0.7691 |
Delgado Vega et al. [20] | Italy | European | 258 | 223 | 0.390 | 0.500 | 0.64 (0.49–0.82) | 5.68 × 10–4 |
Delgado Vega et al. [20] | Spain, | European | 517 | 901 | 0.460 | 0.450 | 1.04 (0.89–1.21) | 0.6064 |
Delgado Vega et al. [20] | Argentina | Latin American | 278 | 355 | 0.350 | 0.440 | 0.69 (0.55–0.87) | 1.59 × 10–3 |
rs10489265 (G allele) | ||||||||
Zhou et al. [13] | China | Asian | 722 | 804 | 0.348 | 0.287 | 1.33 (1.14–1.55) | 3.10 × 10–4 |
Orozco et al. [24] | UK | European | 3962 | 9275 | 0.250 | 0.240 | 1.05 (0.99–1.12) | 0.11 |