Table 6 Multivariable hierarchical linear regression models with HADS-D score as dependent variable (n = 490)
Independent variables | Dependent variable: HADS-D score Beta coefficients (p-value) | ||||
|---|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | |
Socio-demographics | |||||
Being male | − 1.85 (< 0.001) | − 1.42 (0.001) | − 1.41 (0.001) | − 1.41 (0.001) | − 1.18 (0.007) |
RA-related variables | |||||
PhGA | 0.42 (< 0.001) | 0.40 (< 0.001) | 0.35 (< 0.001) | 0.29 (0.002) | |
PGA | 0.06 (0.387) | 0.05 (0.488) | 0.04 (0.582) | 0.05 (0.587) | |
RA therapy | |||||
Corticosteroids | 0.21 (0.547) | − 0.16 (0.657) | − 0.32 (0.383) | ||
NSAIDs (> 10 per month) | 0.55 (0.196) | 0.48 (0.254) | 0.37 (0.382) | ||
Antidepressants | 1.96 (0.007) | 2.06 (0.004) | |||
Total number of drugs | 0.16 (0.035) | 0.10 (0.180) | |||
Disease activity and disability indices | |||||
SDAI | − 0.03 (0.422) | ||||
HAQ | 0.97 (0.002) | ||||
Goodness of fit indices | |||||
Adj R-squared % | 3.3% | 10.7% | 10.7% | 12.9% | 14.5% |
AIC | 2723.9 | 2686.9 | 2688.9 | 2678.3 | 2671.4 |
BIC | 2732.3 | 2703.7 | 2714.1 | 2711.9 | 2713.4 |
LR Chi2 | – | 41.0 | 1.9 | 14.6 | 10.9 |
p > Chi2 | – | < 0.001 | 0.379 | < 0.001 | 0.004 |