Clinical characteristics | Total sample (n = 490) | Depression according to HADS-D (cut-off ≥ 11) | p-value (Chi-square or t test) | |
---|---|---|---|---|
Not depressed (n = 420) | Depressed (n = 70) | |||
Positive personal history for depression, n (%) | 106 (21.6%) | 76 (18.1%) | 30 (42.8%) | < 0.001 |
RF and/or ACPA positive, n (%) | 292 (59.6%) | 246 (58.6%) | 46 (65.7%) | 0.294 |
BMI (kg/m2), mean (sd) | 25.7 (4.8) | 25.7 (4.8) | 26.0 (5.1) | 0.606 |
Smoker, n (%) | 64 (13.1%) | 57 (13.6%) | 7 (10.0%) | 0.565 |
Positive family history for rheumatologic disease, n (%) | 127 (25.9%) | 104 (24.8%) | 23 (32.8%) | 0.184 |
Erosions, n (%) | 212 (43.3%) | 179 (42.6%) | 33 (47.1%) | 0.516 |
Disease duration (years), mean (sd) | 12.5 (9.6) | 12.5 (9.6) | 12.4 (9.5) | 0.931 |
TJC 28, mean (sd) | 2.1 (3.5) | 2.0 (3.5) | 2.6 (3.9) | 0.197 |
SJC 28, mean (sd) | 1.1 (2.2) | 1.1 (2.3) | 1.2 (2.1) | 0.647 |
TJC 68, mean (sd) | 2.6 (4.0) | 2.4 (3.8) | 3.7 (4.9) | 0.011 |
SJC 66, mean (sd) | 1.4 (2.7) | 1.4 (2.7) | 1.7 (2.4) | 0.324 |
PhGA, mean (sd) | 4.4 (2.7) | 4.2 (2.7) | 5.5 (2.5) | < 0.001 |
PGA, mean (sd) | 5.3 (2.4) | 5.1 (2.4) | 6.6 (2.2) | < 0.001 |
VAS pain, mean (sd) | 5.0 (2.7) | 4.8 (2.7) | 6.3 (2.2) | < 0.001 |
ESR, mean (sd) | 19.9 (16.6) | 19.6 (16.6) | 21.9 (16.2) | 0.276 |
CRP, mean (sd) | 5.6 (8.8) | 5.8 (9.3) | 4.2 (4.3) | 0.179 |
Vitamin D, mean (sd) | 68.8 (28.3) | 69.0 (28.1) | 68.1 (30.0) | 0.806 |
Haemoglobin, mean (sd) | 13.4 (1.3) | 13.4 (1.3) | 13.2 (1.3) | 0.105 |