Interstitial or airway abnormalities on HRCT (n = 60) | Absence of Interstitial or airway abnormalities on HRCT (n = 19) | P value | |
---|---|---|---|
Age, median (IQR) | 50 (42–58) | 45 (33–53) | 0.17 |
Female gender, n (%) | 51 (85) | 15 (78.9) | 0.53 |
Month since RA diagnosis, median (IQR) | 3 (1–7) | 2 (0–5) | 0.22 |
Smoking status (past or current), n (%) | 32 (53.3) | 10 (52.6) | 0.95 |
Dyspnea and/or cough, n (%)a | 21 (35) | 4 (21) | 0.25 |
Abnormal physical examination, n (%)b | 13 (21.6) | 0 (0) | 0.026 |
FVC%, mean (SD) | 95.6 (1.69) | 103.6 (2.91) | 0.022 |
FVC% < 80, n (%) | 7 (11.6) | 0 (0) | 0.119 |
VEF1/FVC% < 70, n (%) | 2 (10.53) | 3 (5) | 0.38 |
TCL%, mean (SD) | 106.5 (12.05) | 110.1 (23.4) | 0.39 |
TLC < 80%, n (%) | 1 (1.67) | 0 (0) | 0.57 |
RV/TLC%, mean (SD) | 99.83 (31.5) | 82.05 (30.08) | 0.044 |
RV/TLC% > 120, n (%) | 12 (20) | 0 (0) | 0.034 |
DLCO%, mean (SD) | 91.05 (21.42) | 107.6 (23.4) | 0.009 |
DLCO < 80%, n (%) | 7 (11.67) | 5 (26.3) | 0.121 |
ANA, n (%) | 39 (78) | 9 (64.29) | 0.29 |
RF, n (%) | 44 (86.2) | 14 (93.3) | 0.46 |
ACPA, n (%) | 44 (88) | 16 (100) | 0.146 |
Anti Ro, n (%) | 7/44 (15.9) | 4/13 (30.7) | 0.233 |
ESR, median (IQR) | 31 (22–53) | 27 (15–40) | 0.113 |
RCP, median (IQR) | 1.8 (0.7–8) | 2 (1–12) | 0.71 |
CDAI, median (IQR) | 18 (11–24) | 18 (12–24) | 0.69 |
DAS28, median (IQR) | 4.55 (3.81–5.4) | 4.4 (3.37–4.95) | 0.48 |
HAQ, median (IQR) | 1.37 (0.7–2) | 1 (0.6–1.2) | 0.81 |
Extra articular manifestations, n (%) | 12 (21.6) | 6 (31.5) | 0.37 |