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Table 2 Comparison of characteristics of patients with and without interstitial or airway abnormalities on HRCT

From: Lung involvement prevalence in patients with early rheumatoid arthritis without known pulmonary disease: a multicentric cross sectional study

 

Interstitial or airway abnormalities on HRCT (n = 60)

Absence of Interstitial or airway abnormalities on HRCT (n = 19)

P value

Age, median (IQR)

50 (42–58)

45 (33–53)

0.17

Female gender, n (%)

51 (85)

15 (78.9)

0.53

Month since RA diagnosis, median (IQR)

3 (1–7)

2 (0–5)

0.22

Smoking status (past or current), n (%)

32 (53.3)

10 (52.6)

0.95

Dyspnea and/or cough, n (%)a

21 (35)

4 (21)

0.25

Abnormal physical examination, n (%)b

13 (21.6)

0 (0)

0.026

FVC%, mean (SD)

95.6 (1.69)

103.6 (2.91)

0.022

FVC% < 80, n (%)

7 (11.6)

0 (0)

0.119

VEF1/FVC% < 70, n (%)

2 (10.53)

3 (5)

0.38

TCL%, mean (SD)

106.5 (12.05)

110.1 (23.4)

0.39

TLC < 80%, n (%)

1 (1.67)

0 (0)

0.57

RV/TLC%, mean (SD)

99.83 (31.5)

82.05 (30.08)

0.044

RV/TLC% > 120, n (%)

12 (20)

0 (0)

0.034

DLCO%, mean (SD)

91.05 (21.42)

107.6 (23.4)

0.009

DLCO < 80%, n (%)

7 (11.67)

5 (26.3)

0.121

ANA, n (%)

39 (78)

9 (64.29)

0.29

RF, n (%)

44 (86.2)

14 (93.3)

0.46

ACPA, n (%)

44 (88)

16 (100)

0.146

Anti Ro, n (%)

7/44 (15.9)

4/13 (30.7)

0.233

ESR, median (IQR)

31 (22–53)

27 (15–40)

0.113

RCP, median (IQR)

1.8 (0.7–8)

2 (1–12)

0.71

CDAI, median (IQR)

18 (11–24)

18 (12–24)

0.69

DAS28, median (IQR)

4.55 (3.81–5.4)

4.4 (3.37–4.95)

0.48

HAQ, median (IQR)

1.37 (0.7–2)

1 (0.6–1.2)

0.81

Extra articular manifestations, n (%)

12 (21.6)

6 (31.5)

0.37

  1. aDyspnea greater the I mMRC
  2. bRochus, wheezing or crackles on auscultation, or digital clubbing on examination