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Table 7 Risk factors of pulmonary hypertension, anemia and serositis in SLE flare

From: Risk factors for the flare of systemic lupus erythematosus and its influence on prognosis: a single-center retrospective analysis

  Pulmonary hypertension Anemia associated with SLE Serositis
OR 95%CI OR 95%CI OR 95%CI
Age 1.007 (0.963,1.053) 0.978 (0.946,1.012) 0.979 (0.942,1.018)
Gender 0.000 / 0.480 (0.094,2.446) 0.177 (0.019,1.160)
Disease duration 1.000 (0.993,1.008) 1.002 (0.995,1.008) 1.003 (0.996,1.010)
SLEDAI-2 K 1.024 (0.942,1.113) 1.134 (1.059,1.214)e 1.156 (1.070,1.248)g
Glucocorticoid amount 0.577 (0.105,3.185) 0.784 (0.426,1.442) 0.889 (0.503,1.609)
Hydroxychloroquine 0.704 (0.217,2.290) 1.722 (0.602,4.963) 2.085 (0.637,6.821)
Immunosuppressive therapy 0.883 (0.299,2.606) 0.973 (0.423,2.236) 0.742 (0.294,1.874)
Regular maintenance treatment 0.158 (0.043,0.577)a 0.319 (0.141,0.720)f 0.362 (0.145,0.908)h
Maintenance therapy < 1 years 4.000 (1.232,12.989) b 0.687 (0.205,2.299) 5.764 (1.642,20.241) i
Maintenance therapy < 2 years 3.208 (1.129,9.115) c 0.799 (0.288,2.216) 2.283 (0.759,6.684)
Maintenance therapy < 3 years 2.986 (1.087,8.202)d 0.734 (0.266,2.022) 1.745 (0.584,5.215)
Maintenance therapy < 4 years 2.252 (0.627,8.089) 0.776 (0.254,2.374) 1.335 (0.403,4.420)
  1. a:P = 0.005; b:P = 0.021; c: P = 0.029; d: P = 0.034; e: P < 0.001; f: P = 0.006; g: P < 0.001; h: P = 0.030; i:P = 0.006; SLEDAI-2 K Systemic lupus erythematosus disease activity index-2000