Table 1 Demographic, clinical and serological data for both patients with gout and controls

Male/Female

175/21

133/13

42/8

0.161

115/10

94/7

21/3

0.627

60/11

39/6

21/5

0.508

Age (years)

54.54 ± 17.27

56.02 ± 16.98

50.20 ± 17.52

0.163

56.16 ± 16.93

56.65 ± 16.65

54.08 ± 18.28

0.441

51.68 ± 17.59

54.60 ± 17.81

46.62 ± 16.31

0.065

Disease duration (yrs)

6.36 ± 7.07

7.60 ± 7.56

2.75 ± 3.48

0.031

7.52 ± 7.94

8.69 ± 8.27

2.63 ± 3.42

<0.001

4.32 ± 4.59

5.07 ± 4.92

2.95 ± 3.64

0.049

Tophus (n, %)

33 (16.8)

33 (22.6)

0

<0.001*

20 (16.0)

20 (19.8)

0

0.013*

13 (18.3)

13 (28.9)

0

0.001*

Erosive disease (n, %)

79 (40.3)

73 (50.0)

6 (12.0)

<0.001

60 (48.0)

57 (56.4)

3 (12.5)

<0.001

19 (26.8)

16 (35.6)

3 (11.5)

0.054

IHD (n, %)

74 (37.8)

61 (41.8)

13 (26.0)

0.047

47 (37.6)

41 (40.6)

1 (25.0)

0.156

27 (38.0)

20 (44.4)

7 (26.9)

0.143

Hypertension (n, %)

113 (57.7)

93 (63.7)

20 (40.0)

0.003

75 (60)

65 (64.4)

10 (41.7)

0.041

38 (53.5)

28 (62.2)

10 (38.5)

0.053

Type II diabetes (n, %)

84 (42.9)

68 (46.6)

16 (32.0)

0.072

56 (44.8)

49 (48.5)

7 (29.2)

0.087

28 (39.4)

19 (42.2)

9 (34.6)

0.527

Dyslipidemia (n, %)

10 (5.1)

9 (6.2)

1 (2.0)

0.434

47 (37.6)

41 (40.6)

6 (25.0)

0.841

1 (1.4)

1 (2.2)

0 (0)

1.000*

Diuretic use (n, %)

39 (19.9)

38 (26.0)

1 (2.0)

0.001

23 (18.4)

23 (22.8)

0

0.007*

16 (22.5)

15 (33.3)

1 (3.8)

0.010

ULT at time of DECT (n, %)

37 (18.9)

35 (24.0)

2 (4.0)

0.004

22 (17.6)

21 (20.8)

1 (4.2)

0.104

15 (21.1)

14 (31.1)

1 (3.8)

0.016

BMI ≥ 28 (n, %)

32 (16.3)

22 (15.1)

10 (20.0)

0.415

21 (16.8)

18 (17.8)

3 (12.5)

0.747

11 (15.5)

4 (8.9)

7 (26.9)

0.092

serum uric acid at time of DECT, (μmol/L)

456.11 ± 123.16

471.69 ± 119.96

410.64 ± 122.29

0.003

451.54 ± 117.82

466.61 ± 114.98

388.08 ± 110.24

0.005

466.42 ± 126.56

486.62 ± 120.73

431.46 ± 131.11

0.096

serum uric acid at time of DECT with ULT, (μmol/L)

435.81 ± 146.94

443.37 ± 145.37

303.50 ± 147.79

0.243

399.73 ± 143.50

409.29 ± 139.69

199.00

0.091

475.40 ± 133.0

480.21 ± 136.71

408.00

0.933

serum uric acid at time of DECT without ULT, (μmol/L)

459.21 ± 118.43

480.62 ± 110.00

415.10 ± 120.90

0.001

462.60 ± 109.24

481.66 ± 103.41

396.30 ± 104.93

0.004

464.02 ± 125.91

489.52 ± 115.11

432.40 ± 133.73

0.081

eGFR

0.012

0.058

0.014

 eGFR>90 (n, %)

96 (49.0)

64 (43.8)

32 (64.0)

63 (50.4)

49 (48.5)

14 (58.3)

33 (46.5)

15 (33.3)

18 (69.2)

 eGFR60–90 (n, %)

64 (32.7)

49 (33.6)

15 (30.0)

42 (33.6)

32 (31.7)

10 (41.7)

22 (31.0)

17 (37.8)

5 (19.2)

 eGFR<60 (n, %)

36 (18.4)

33 (22.6)

3 (6.0)

20 (16.0)

20 (19.8)

0

16 (22.5)

13 (28.9)

3 (11.5)