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Table 5 Distribution of nuclear, nucleolar, cytoplasmic and mitotic apparatus patterns according to the relevance perceived by rheumatologists in different Brazilian macro-regions

From: Rheumatologist perspective of the Brazilian consensus for detection of auto antibodies in HEp-2 CELLS

Macro-region

N

NE

CO

S

SE

SR

Total

Total

18 (4%)

72 (17%)

37 (9%)

52 (13%)

230 (56%)

5 (1%)

414 (100%)

Nuclear patterns

 Reticular coarse

28%a

28%

24%

40%

34%

20%

32%

Quasi-homogeneous

17%

29%

35%

33%

17%

20%

23%

 Homogenous

78%

83%

78%

71%

79%

40%

78%

 Dense fine speckled

39%

33%

35%

23%

30%

60%

31%

 Centromere

44%

63%

59%

75%

67%

20%

65%

 Fine speckled

56%

56%

49%

58%

56%

40%

55%

 Large/coarse speckled

83%

82%

62%

75%

71%

40%

73%

 Multiple nuclear dots

6%

8%

14%

10%

5%

0%

7%

 Smooth/Punctate nuclear envelope

11%

8%

8%

13%

11%

0%

10%

 Pleomorfic/PCNA

6%

14%

11%

13%

16%

0%

14%

 Not familiar with the patterns

0%

0%

0%

0%

1%

0%

1%

 Considers the patterns unimportant

0,5%

1%

0%

0%

0%

0%

0%

 Did not answer

11%

7%

19%

13%

14%

40%

13%

Nucleolar patterns

 Homogeneous nucleolar

67%

58%

70%

67%

61%

40%

62%

 Clumpy nucleolar

11%

13%

24%

19%

22%

40%

20%

 Punctate nucleolar

44%

43%

49%

40%

43%

60%

44%

 Not familiar

6%

8%

5%

8%

10%

0%

9%

 Unimportant

0%

4%

0%

0%

0%

0%

1%

 Did not answer

17%

11%

19%

15%

15%

40%

15%

Cytoplasmic patterns

 Fibrillar linear

17%

14%

8%

21%

14%

0%

14%

 Fibrillar filamentous

6%

11%

14%

19%

9%

0%

11%

 Fibrillar segmental

6%

8%

5%

13%

10%

0%

9%

 Discrete dots

17%

14%

19%

19%

18%

0%

17%

 Dense fine speckled

22%

32%

30%

21%

29%

20%

28%

 Fine speckled

17%

33%

35%

27%

42%

20%

36%

 Reticular/AMA

22%

33%

35%

40%

30%

60%

33%

 Polar speckled

6%

14%

14%

17%

9%

20%

11%

 Rods and rings

6%

28%

22%

19%

13%

0%

17%

 Not familiar with the patterns

6%

13%

11%

17%

18%

0%

16%

 Considers unimportant the patterns

11%

57%

0%

2%

0%

0%

2%

 Did not answer

17%

13%

19%

15%

17%

40%

17%

Mitotic patterns

 Spindle fibers

0%

24%

32%

19%

38%

40%

31%

 Centrosome

11%

19%

24%

25%

18%

20%

19%

 Spidle fibers NuMA II

28%

32%

27%

40%

31%

0%

32%

 Intercellular bridge

6%

21%

8%

17%

11%

20%

13%

 Not familiar with the patterns

33%

31%

14%

29%

26%

20%

26%

 Considers unimportant the patterns

6%

13%

0%

2%

0%

0%

3%

 Did not answer

22%

14%

22%

17%

19%

40%

18%

  1. a Frequency of participants who consider the pattern relevant (in brackets the percentage relative to the total number of participants who answered this question in the respective region of the country)
  2. N North, NE Northeast; CO Midwest; S South; SE Southeast, SR No region