Fig. 3

Decreased expression of miR-126-5p enhances the viability and migratory ability of chondrocytes, and represses ECM degradation in CHON-001 cells. a Relative expression of miR-126-5p was determined by qRT-PCR in CHON-001 cells. ^***P < 0.001, vs. mimics NC. ^###P < 0.001, vs. inhibitor NC. b The cell viability was determined by MTT assay in CHON-001 cells. ^***P < 0.001, vs. mimics NC. ^###P < 0.001, vs. inhibitor NC. c Relative migration was assessed by transwell assay in CHON-001 cells. ^**P < 0.01, vs. mimics NC. ^##P < 0.01, vs. inhibitor NC. d Relative protein expression of collagen II and MMP13 was determined by western blot in CHON-001 cells. ^**P < 0.01, ^***P < 0.001, vs. mimics NC. ^###P < 0.001, vs. inhibitor NC