Table 1 Characteristics of individual studies included
From: Association of homocysteine with ankylosing spondylitis: a systematic review and meta-analysis
First author, year | Region | AS | Control | Â | Â | Â | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Age (year) (mean ± sd) | BMI | Sex ratio (M/F) | BASDAI | Duration (year) (mean ± sd) | Age (year) (mean ± sd) | BMI | Sex ratio (M/F) | Assay method, sample | Study type | Criteria for the classification | NOS | ||
Shu JL, 2020 [16] | Mainland China | 41.6 ± 8.6 | NA | 30/5 | NA | NA | 39.7 ± 14.4 | NA | 36/5 | NA | CS | ACR | 7 |
Geçene M, 2013 [39] | Turkey | 36.7 ± 4.8 | 24.9 ± 3.1 | 50/0 | 2.4 ± 1.7 | NA | 36.3 ± 4.7 | 25.0 ± 3.0 | 50/0 | HPLC, plasma | CS | ACR | 7 |
Mao N, 2012 [34] | Mainland China | NA | NA | NA | NA | NA | NA | NA | NA | ELISA, plasma | CS | ACR | 7 |
Capkin E, 2012 [40] | Turkey | 36.4 ± 11.2 | NA | 88/20 | 3.7 ± 1.6 | 8.4 ± 5.6 | 38.2 ± 13.0 | NA | 49/16 | ELISA, plasma | CS | ACR | 7 |
Başkan BM, 2009 [35] | Turkey | 40.1 ± 11.0 | NA | NA | 4.2 ± 1.7 | 10.0 ± 7.7 | 38.1 ± 0.6 | NA | NA | NA | CS | ACR | 7 |
Gonzalez-Lopez L, 2008 [36] | Mexico | 39.9 ± 8.4 | 26.0 ± 2.8 | 73/24 | 5.4 ± 2.1 | 7.8 ± 6.0 | 38.9 ± 7.8 | 25.8 ± 4.2 | 73/24 | FPIA, Serum | CSS | ACR | 8 |
Wei JC, 2007 [37] | Taiwan, China | NA | NA | NA | NA | NA | NA | NA | NA | ELISA, plasma | CSS | ACR | 7 |
Malesci D, 2007 [41] | Italy | 47.6 ± 11.8 | 29.5 ± 4.4 | 21/3 | 2.7 ± 1.8 | 18.5 ± 10.8 | 49.6 ± 6.0 | NA | 16/3 | NA | CS | ACR&ESSG | 8 |
Xu XY, 2005 [38] | Mainland China | 32.1 ± 13.7 | NA | 44/16 | NA | NA | 30.8 ± 19.7 | NA | 30/32 | FPIA, plasma | CS | ACR | 7 |