Fig. 4

Clinical Outcomes over 5-year follow-up after transplantation. a Modified Rodnan’s Skin Score before and periodically after autologous hematopoietic stem cell transplantation (HSCT). * indicates significant diferences between baseline (PRE) and post-HSCT time points: PRE vs 6 months, p = 0.007; PRE vs 12 months, p = 0.0006; PRE vs 24, 36, 48 and 60 months, p < 0.0001. b Predicted forced vital capacity (FVC) percentages before and periodically after autologous HSCT in all patients included in the study. c Predicted percentages of diffusing capacity of lung carbon monoxide (DLCO) before and periodically after autologous HSCT in all patients included in the study. d Predicted FVC percentages before and periodically after autologous HSCT in the subset of patients with progressive interstitial lung disease at enrollment for transplantation. e Predicted percentages of diffusing capacity of lung carbon monoxide (DLCO) before and periodically after autologous HSCT in patients with progressive interstitial lung disease at enrollment for transplantation. Box plot limits indicate 25th to 75th percentiles; lines within boxes indicate the median and whiskers mark the 10th and the 90th percentiles