Table 1 Baseline clinical and demographic characteristics in PP population
Baseline characteristics | GS/CS (N = 209) | RP (N = 223) |
|---|---|---|
Female, n (%) | 184 (88) | 193 (86.6) |
Age, mean (sd), years | 62.8 (8.9) | 63 (8) |
Caucasian, n (%) | 133 (63.6) | 133 (59.6) |
Osteoarthritis duration, mean (sd), years | 7.7 (6.9) | 7.4 (5.7) |
BMI, mean (sd), kg/m2 | 30.4 (4.7) | 30.7 (4.4) |
Kellgren-Lawrence grading, n (%) | ||
II | 146 (69.9) | 151 (67.7) |
III | 63 (30.1) | 72 (32.3) |
Overall assessment of OA by the patient, mean (sd), VAS 0-100 mm | 66.7 (18.1) | 65 (19.2) |
Overall assessment of OA by the physician, mean (sd), VAS 0-100 mm | 61.8 (12.5) | 62.9 (14.1) |
WOMAC, mean (sd), mm | ||
Pain subscale | 66.3 (13.2) | 68.1 (13.5) |
Stiffness subscale | 64.9 (21.1) | 65.4 (20.9) |
Physical function subscale | 65.7 (13.7) | 65.4 (14.6) |
Total score | 196.9 (39.9) | 198.9 (41.7) |
SF-12, mean (sd) | ||
Physical component | 34.9 (7.4) | 35.7 (7.5) |
Mental component | 49 (10.6) | 46.9 (11.3) |
Comorbidities (reported by ≥ 5% of patients), n (%) | ||
Back pain | 56 (25.8) | 61 (27.4) |
Musculoskeletal pain / Arthralgia / Pain in the extremities | 46 (22) | 46 (20.6) |
Osteoporosis/ Osteopenia | 34 (16.3) | 30 (13.5) |
Dyslipidemia / Hypercholesterolemia | 69 (33) | 70 (31.4) |
Impaired glucose tolerance | 33 (15.8) | 40 (17.9) |
Headache / Migraine | 60 (28.7) | 77 (34.5) |
Hypothyroidism | 40 (19.1) | 39 (17.5) |
Gastritis | 26 (12.4) | 30 (13.5) |
Gastroesophageal reflux disease | 9 (4.3) | 14 (6.3) |
Depression | 13 (6.2) | 17 (7.6) |
Insomnia | 11 (5.3) | 15 (6.7) |
Systemic arterial hypertension | 128 (61.2) | 130 (58.3) |
Lower limbs varices | 44 (21.1) | 69 (30.9) |