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Table 5 Comparison of obstetric outcomes in Takayasu arteritis across the world

From: Poor obstetric outcomes in Indian women with Takayasu arteritis

Centre (year of publication)No of PregnanciesHypertensionFetal complicationsLive birth- n (%)Maternal mortalityWong’s scoringDisease activeControlsConclusion
Wong et al., Hong Kong (1983) [17]1916 (84.2%)9 (60%)15 (78.9%)1 (5.2%)- MIYes0Yes-TA before diagnosisIUGR can be predicted by scoring system
PGI Chandigarh, India(2000) [12]2422 (91.7%)9 (52.9%)17 (70.8%)0NoNANoAbdominal vessel disease & delay in care predict poor outcomes
University de Estado, Brazil (2012) [18]117 (63.6%)7 (63.6%)11 (100%)0No0NoClose monitoring with combined care is usedful; No disease activity seen during pregnancy
IPGMER, Kolkata, India (2012) [14]2929 (100%)20 (86.9%)23 (89.7%)1 (5.8%)- CVAYesNAYes- HealthyConception usually spontaneous, Disease not active
Osaka, Japan (2014) [19]275 (18.5%)4 (14.8%)27 (100%)0No3NoIshikawa stage II fares worse
Istanbul University, Turkey (2015) [20]193 (16%)1 (5.2%)19 (100%)0No2 (10.5%)Yes-TA before diagnosisTA pregnancies have favorable outcome
Multicentre Paris, France (2015) [21]9826 (27%)13 (16.7%)78 (79.6%)0No6 (6.1%)Yes-TA before diagnosisSmoking and NIH score > 1 predict poor outcomes
CMC, Vellore, India [22]167 (43.8%)7 (43.8%)16 (100%)0NA4 (25%)NoGood outcomes are seen in type V disease when in remission
Multicentric, Oslo, Norway (2017) [9]3717 (29.3)12(32%)25 (68)0 (1 had stroke)No10(60%)Yes-TA before diagnosisMaternal and foetal outcomes were favourable.
Tel Aviv, Israel (2018) [23]208/13 (61.5%)9(45%)13 (65%)0NoNANoTargeted treatment of high blood pressure emphasised
Ankara, Turkey (2019) [24]228 (36.4)18 (81.8%)16 (72.7%)0No5 relapsed during pregnancyNoAlmost half had disease relapse during pregnancy
Current study, Lucknow, India3815 (39.5%)12 (63.2%)19 (50%)0Yes15 (7.25–18)aYes-TA before diagnosisWong’s score useful, ITAS needs evaluation in larger cohort
  1. MI myocardial infarction, NA Not available, NIH National Institute of Health indices index
  2. aMedian (IQR) CVA, cerebrovascular accident