Table 5 Comparison of obstetric outcomes in Takayasu arteritis across the world
From: Poor obstetric outcomes in Indian women with Takayasu arteritis
Centre (year of publication) | No of Pregnancies | Hypertension | Fetal complications | Live birth- n (%) | Maternal mortality | Wong’s scoring | Disease active | Controls | Conclusion |
|---|---|---|---|---|---|---|---|---|---|
Wong et al., Hong Kong (1983) [17] | 19 | 16 (84.2%) | 9 (60%) | 15 (78.9%) | 1 (5.2%)- MI | Yes | 0 | Yes-TA before diagnosis | IUGR can be predicted by scoring system |
PGI Chandigarh, India(2000) [12] | 24 | 22 (91.7%) | 9 (52.9%) | 17 (70.8%) | 0 | No | NA | No | Abdominal vessel disease & delay in care predict poor outcomes |
University de Estado, Brazil (2012) [18] | 11 | 7 (63.6%) | 7 (63.6%) | 11 (100%) | 0 | No | 0 | No | Close monitoring with combined care is usedful; No disease activity seen during pregnancy |
IPGMER, Kolkata, India (2012) [14] | 29 | 29 (100%) | 20 (86.9%) | 23 (89.7%) | 1 (5.8%)- CVA | Yes | NA | Yes- Healthy | Conception usually spontaneous, Disease not active |
Osaka, Japan (2014) [19] | 27 | 5 (18.5%) | 4 (14.8%) | 27 (100%) | 0 | No | 3 | No | Ishikawa stage II fares worse |
Istanbul University, Turkey (2015) [20] | 19 | 3 (16%) | 1 (5.2%) | 19 (100%) | 0 | No | 2 (10.5%) | Yes-TA before diagnosis | TA pregnancies have favorable outcome |
Multicentre Paris, France (2015) [21] | 98 | 26 (27%) | 13 (16.7%) | 78 (79.6%) | 0 | No | 6 (6.1%) | Yes-TA before diagnosis | Smoking and NIH score > 1 predict poor outcomes |
CMC, Vellore, India [22] | 16 | 7 (43.8%) | 7 (43.8%) | 16 (100%) | 0 | NA | 4 (25%) | No | Good outcomes are seen in type V disease when in remission |
Multicentric, Oslo, Norway (2017) [9] | 37 | 17 (29.3) | 12(32%) | 25 (68) | 0 (1 had stroke) | No | 10(60%) | Yes-TA before diagnosis | Maternal and foetal outcomes were favourable. |
Tel Aviv, Israel (2018) [23] | 20 | 8/13 (61.5%) | 9(45%) | 13 (65%) | 0 | No | NA | No | Targeted treatment of high blood pressure emphasised |
Ankara, Turkey (2019) [24] | 22 | 8 (36.4) | 18 (81.8%) | 16 (72.7%) | 0 | No | 5 relapsed during pregnancy | No | Almost half had disease relapse during pregnancy |
Current study, Lucknow, India | 38 | 15 (39.5%) | 12 (63.2%) | 19 (50%) | 0 | Yes | 15 (7.25–18)a | Yes-TA before diagnosis | Wong’s score useful, ITAS needs evaluation in larger cohort |