Neutrophil/lymphocyte and platelet/lymphocyte ratios as potential markers of disease activity in patients with Ankylosing spondylitis: a case-control study

Table 2 Laboratory parameters of study groups based on disease activity

	Control (n = 81)	BASDAI< 4 (n = 77)	BASDAI≥4 (n = 55)	P value
White blood cell count (10⁹/L)	7.31 ± 1.49	7.85 ± 1.65	8.56 ± 1.81	< 0.001 P1 = 0.097 P2 < 0.001 P3 = 0.040
Neutrophil count (10⁹/L)	4.51 ± 0.98	4.53 ± 1.33	5.30 ± 1.51	0.001 P1 = 0.994 P2 = 0.001 P3 = 0.002
Lymphocyte count (10⁹/L)	2.30 ± 0.51	2.76 ± 0.76	2.65 ± 0.92	< 0.001 P1 < 0.001 P2 = 0.019 P3 = 0.661
Platelet count (10⁹/L)	263.08 ± 50.56	257.58 ± 62.38	331.96 ± 103.22	< 0.001 P1 = 0.879 P2 < 0.001 P3 < 0.001
NLR	2.02 ± 0.55	1.77 ± 0.73	2.31 ± 1.23	0.002 P1 = 0.138 P2 = 0.131 P3 = 0.001
PLR	99.32 ± 33.97	119.24 ± 32.49	142.04 ± 70.98	< 0.001 P1 = 0.019 P2 = 0.014 P3 < 0.001
ESR (mm/hr.)	1.40 ± 3.48	15.31 ± 33.23	12.31 ± 25.86	< 0.001 P1 < 0.001 P2 = 0.013 P3 < 0.001

AS, ankylosing spondylitis; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; ESR, erythrocyte sedimentation rate; n, number; NLR, neutrophil/lymphocyte ratio; PLR, platelet/lymphocyte ratio; P value, probability value (< 0.05); P1, Control vs. BASDAI < 4; P2, Control vs. BASDAI ≥4; P3, BASDAI ≥4 vs. BASDAI < 4
Comparisons of parametric data of three groups were performed with One-Way ANOVA test. Post-hoc Tukey Test was used for differences between the three groups

ISSN: 2523-3106