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Table 1 Mixed effects analysis of group effects (Fibromyalgia vs. Healthy Control) and time effects (Baseline, 3 Applications, 6 Applications, 3 Months) as well as interaction. A significant interaction effect indicates differences in value development/performance over time depending on the cohort

From: Serial whole-body cryotherapy in fibromyalgia is effective and alters cytokine profiles

 

Group Effect

Time Effect

Interaction

IL1

p <  0.0001

p <  0.0001

p <  0.0001

IL6

p = 0.0005

p = 0.0009

p = 0.0053

IL10

p = 0.0008

p = 0.0032

p <  0.0001

TNF-alpha

p = 0.0096

p = 0.8783

p = 0.1271

VAS

–

p <  0.0001

–

FIQ

–

p <  0.0001

–

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Advances in Rheumatology

ISSN: 2523-3106