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Table 4 Historical criteria background for saliva production in Sjögren’s syndrome diagnosis

From: Unstimulated whole salivary flow in Sjögren’s Syndrome: systematic literature review and meta-analysis

Author

Year

Objective dry mouth evaluation included for diagnosis.

Value

Daniels et al.

1975

There are no established objective criteria for determining the presence of the oral component of SS.

NA

Manthorpe et al.

1975–1976

No

NA

Skopoul et al.

1986

No, they mention subjective xerostomia and stimulated modified whole sialometry

NA

Fox et al.

1986

No

Just mention decreased basal and stimulated salivary flow rate

Vitali et al.

1993

Objective evidence of salivary gland involvement determined based on a positive result from at least 1 of the following 3 tests: Salivary scintigraphy, parotid sialography, USF.

USF ≤1,5 ml/15 min

Fujibayashi et al.

1999

Optional in an item, gum or Saxon test

NA

Vitali et al.

2002

Yes

UWSF ≤1,5 ml/15 min

Fujibayashi et al.

2004

Yes

Flow rate ≤10 ml/10 min

Shiboski et al.

2012

No

NA

Shiboski et al.

2016

Yes

UWSF ≤0,1 ml/min

  1. NA Not available, USF Unstimulated Salivary Flow, UWSF Unstimulated Whole Salivary Flow