Fig. 6

Purine metabolism of gut microbiota (a) and liver [XOD activity (b); ADA activity (c)] of mice in the four groups. Gene functional categories were from level 3 of KEGG pathways and involved in purine metabolism. “ns” represents not significant; “*” represents p < 0.05 in comparison with CT; and “**” represents p < 0.01 in comparison with CT; “+” represents p < 0.05 in comparison with CGM; and “++” represents p < 0.01 in comparison with CGM. CT: control group; HFD: hyperuricaemia model; MSU: acute gout model; CGM: compound gout model