Fig. 4

Alterations of alpha diversity indexes [Shannon (a); Chao1 (b)], PCoA score plot (c) and main phyla (d, e and f) of mice in the four groups. “ns” represents not significant; “*” represents p < 0.05 in comparison with CT; and “**” represents p < 0.01 in comparison with CT; “+” represents p < 0.05 in comparison with CGM; and “++” represents p < 0.01 in comparison with CGM. CT: control group; HFD: hyperuricaemia model; MSU: acute gout model; CGM: compound gout model