Table 2 ADRs of bDMARDs in patients with JIA, JSLE and JDM
| Â | Medications | ||||||
|---|---|---|---|---|---|---|---|
ETN | ADA | IFX | TCZ | ABA | RTX | TOTAL | |
Patients on MED | 54 | 49 | 36 | 9 | 7 | 10 | 165 |
Patients on MED with ADR | 10 | 6 | 11 | 2 | – | 1 | 30 |
Patients on MED with ADR(%) | 18.5 | 12.2 | 30.5 | 22.2 | – | 10 | 18.2 |
Infections | – | – | 1 | – | – | 1 | 2 |
Blood and lymphatic system disorders: | |||||||
 - Thrombocytopenia | – | – | 1 | – | – | – | 1 |
Nervous system disorders: | |||||||
 - Headache/dizziness/discomfort | – | – | 1 | – | – | – | 1 |
Eye disorders: | |||||||
 - Uveitis | 2 | 1 | – | – | – | – | 3 |
Gastrointestinal disorders: | |||||||
 - Nausea/vomiting | 2 | 3 | 1 | – | – | – | 6 |
 - Epigastric pain | – | 1 | – | – | – | – | 1 |
Hepatobiliary disorders: | |||||||
 -↑ liver enzymes | – | – | – | 1 | – | – | 1 |
Skin and subcutaneous tissue disorders: | |||||||
 - Atopic dermatitis | 1 | – | – | – | – | – | 1 |
 - Psoriasis | – | 1 | – | – | – | – | 1 |
 - Urticaria | – | – | 3 | 1 | – | – | 4 |
Renal and urinary disorders: | |||||||
 - Nephritis | 1 | – | – | – | – | – | 1 |
 - Hematuria | – | 1 | – | – | – | – | 1 |
General disorders and administration site conditions: | |||||||
 - Anaphylaxis | – | – | 2 | – | – | – | 2 |
 - Local reactions and pain | 5 | 1 | 2 | – | – | – | 8 |
Total number of ADRs | 11 | 8 | 11 | 2 | – | 1 | 33 |