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Table 1 Clinical and laboratory characteristics of APS patients included, according to HD diagnosis

From: Anorectal diseases in patients with Antiphospholipid syndrome: a cross-sectional study

  Hemorrhoidal Disease (N = 17) No Hemorrhoidal Disease (N = 24) p-value
Demographic characteristics
 Female gender (N, %) 17 (100%) 24 (100%)
 Age (Median, IQR) 49 (39–53) 41.5 (33.25–45) 0.09
Risk factors possibly related to HD
 Body Mass Index (Median, IQR) 29.9 (25.8–35.2) 28.57 (25.14–30.99) 0.223
 Obesity (N, %) 8 (47.1%) 7 (29.2%) 0.241
 Pregnancy (ever; N,%) 15 (88.2%) 15 (62.5%) 0.067
 Constipation (N,%) 9 (52.9%) 6 (25%) 0.067
 Family history of HD (N,%) 8 (47.1%) 7 (29.2%) 0.241
APS clinical and serological characteristics
 Arterial thrombosis (N,%) 7 (41.2%) 8 (33.3%) 0.607
 Venous thrombosis (N,%) 11 (64.7%) 16 (66.7%) 0.896
 Lupus anticoagulant (N,%) 13 (76.5%) 14 (58.3%) 0.130
 Anticardiolipin (N,%) 4 (23.5%) 3 (12.5%) 0.355
 Anti-ß2-glycoprotein I (N,%) 5 (71.4%) 7 (77.8%) 0.771
 Triple positivity (N,%) 1 (5.9%) 1 (4.2%) 0.715
Anorectal symptoms/signs
 Rectal exteriorization during defecation 15 (88.2%) 13 (54.2%) 0.021*
 Increased evacuation effort 11 (64.7%) 11 (45.8%) 0.233
 Anal discomfort 8 (47.1%) 4 (16.7%) 0.035*
 Pain during defecation 6 (35.3%) 9 (37.5%) 0.885
 Anal burning 6 (35.3%) 4 (16.7%) 0.171
 Plicoma 5 (29.4%) 11 (45.8%) 0.288
 Bleeding 5 (29.4%) 3 (12.5%) 0.178
 Anal itching 4 (23.5%) 5 (20.8%) 0.837
 Anal Fissure 1 (5.9%) 4 (16.7%) 0.299
  1. APS Antiphospholipid syndrome, HD Hemorrhoidal diseases, IQR Interquartile range. *p < 0.05