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Table 2 Prevalence of MTX-related symptoms in MTX-tolerant and MTX-intolerant patients

From: High frequency of methotrexate intolerance in longstanding rheumatoid arthritis: using the methotrexate intolerance severity score (MISS)

Symptoms MTX-intolerant N = 26 (%) MTX-tolerant N = 94 (%)
Abdominal pain
After taking MTX 12 (46.15) 3 (3.19)
Anticipatory 2 (7.69) 2 (2.12)
Associative 3 (11.53) 1 (1.06)
Nausea
After taking MTX 24 (92.30) 44 (46.80)
Anticipatory 18 (69.23) 7 (7.44)
Associative 22 (84.61) 13 (13.82)
Vomiting
After taking MTX 8 (30.76) 9 (9.57)
Anticipatory 2 (7.69) 1 (1.06)
Behavioral complaints
Restlessness 20 (76.92) 10 (10.63)
Crying 11 (42.30) 1 (1.06)
Irritability 20 (76.92) 7 (7.44)
Refusal of MTX 16 (61.53) 4 (4.25)
  1. MTX Methotrexate