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Table 2 Prevalence of MTX-related symptoms in MTX-tolerant and MTX-intolerant patients

From: High frequency of methotrexate intolerance in longstanding rheumatoid arthritis: using the methotrexate intolerance severity score (MISS)

Symptoms

MTX-intolerant N = 26 (%)

MTX-tolerant N = 94 (%)

Abdominal pain

After taking MTX

12 (46.15)

3 (3.19)

Anticipatory

2 (7.69)

2 (2.12)

Associative

3 (11.53)

1 (1.06)

Nausea

After taking MTX

24 (92.30)

44 (46.80)

Anticipatory

18 (69.23)

7 (7.44)

Associative

22 (84.61)

13 (13.82)

Vomiting

After taking MTX

8 (30.76)

9 (9.57)

Anticipatory

2 (7.69)

1 (1.06)

Behavioral complaints

Restlessness

20 (76.92)

10 (10.63)

Crying

11 (42.30)

1 (1.06)

Irritability

20 (76.92)

7 (7.44)

Refusal of MTX

16 (61.53)

4 (4.25)

  1. MTX Methotrexate