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Table 2 Comparison of subjective pain measures in FMS Sham-rTMS and Real-rTMS group

From: Repetitive transcranial magnetic stimulation of the prefrontal cortex for fibromyalgia syndrome: a randomised controlled trial with 6-months follow up

 

Pre-rTMS

Post-rTMS

Follow-up

FU-1 (15-days)

FU-2 (3-months)

FU-3 (6-months)

MPQ: Sensory

Sham

23.0 (17.0–26.5)

20.0 (17.0–24.5)

22.0 (20.0–23.0)

22.0 (21.0–23.0)

22.0 (20.0–24.0)

Real

23.0 (21.0–26.0)

23.0 (18.3–26.8)

21.0 (18.0–26.0)

22.0 (18.0–25.5)

22.0 (18.0–28.0)

p*

0.40

0.29

0.89

0.72

0.74

MPQ: Affective-motivational

 Sham

8.0 (4.5–9.0)

7.0 (4.0–8.0)

6.0 (4.0–8.0)

6.0 (4.0–8.0)

6.0 (5.0–7.5)

 Real

7.0 (5.0–8.0)

3.0 (3.0–4.0)##

4.0 (3.0–4.5)

4.0 (3.0–5.0)

4.0 (3.0–5.0)

 p*

0.10

0.001

0.001

0.001

0.001

MPQ: Evaluative

 Sham

3.0 (3.0–3.5)

3.0 (2.0–3.5)

3.0 (2.0–3.5)

2.0 (1.0–3.5)

3.0 (2.0–4.0)

 Real

3.0 (3.0–4.0)

2.0 (1.0–2.0)##

2.0 (1.0–2.0)

2.0 (1.0–2.0)

2.0 (1.0–2.0)

 p*

0.33

0.001

0.001

0.004

0.001

MPQ: Miscellaneous

 Sham

9.0 (4.25–10.75)

7.0 (5.0–8.0)

7.0 (4.0–9.0)

7.0 (5.0–9.0)

7.0 (5.0–9.0)

 Real

7.0 (4.0–9.0)

6.0 (4.0–9.0)

5.0 (3.0–9.0)

6.0 (3.5–9.0)

7.0 (4.0–10.0)

 p*

0.34

0.33

0.51

0.45

0.95

MPQ: Total score

 Sham

39.0 (36.0–44.0)

39.0 (33.0–45.0)

38.0 (34.0–41.5)

39.0 (34.5–41.0)

38.0 (32.5–41.0)

 Real

39.0 (36.0–44.5)

20.0 (16.0–29.5) ##

20.0 (17.0–30.0)

20.0 (17.0–30.0)

21.0 (18.0–29.0)

 p*

0.87

0.001

0.001

0.001

0.001

MPQ: Present pain intensity

 Sham

3.0 (2.0–3.0)

2.0 (1.0–2.0)

2.0 (2.0–3.0)

2.0 (2.0–3.0)

2.0 (2.0–3.0)

 Real

3.0 (2.0–4.0)

1.0 (1.0–2.0)##

2.0 (1.0–2.0)

2.0 (1.0–2.0)

2.0 (1.0–2.0)

 p*

0.60

0.001

0.001

0.001

0.001

WHOQOL-BREF: Physical

 Sham

38.0 (38.0–44.0)

43.0 (38.0–50.0)

44.0 (38.0–47.0)

44.0 (38.0–50.0)

44.0 (38.0–47.0)

 Real

38.0 (31.0–50.0)

44.0 (38.0–56.0) #

47.0 (40.0–62.0)

44.0 (40.0–56.0)

44.0 (38.0–56.0)

 p*

0.59

0.05

0.05

0.05

0.05

WHOQOL-BREF: Psychological

 Sham

56.0 (38.0–69)

59.0 (38.0–75.0)

44.0 (44.0–69.0)

56.0 (38.0–69.0)

56.0 (44.0–75.0)

 Real

56.0 (44.0–56.0)

69.0 (56.0–75.0) #

69.0 (56.0–75.0)

58.0 (56.0–69.0)

69.0 (56.0–69.0)

 p*

0.74

0.002

0.004

0.04

0.05

WHOQOL-BREF: Social

 Sham

44.0 (44.0–56.0)

50.0 (44.0–56.0)

44.0 (44.0–56.0)

44.0 (43.0–56.0)

50.0 (44.0–56.0)

 Real

50.0 (31.0–69.0)

56.0 (44.0–69.0) #

56.0 (53.0–69.0)

56.0 (47.0–69.0)

56.0 (50.0–69.0)

 p*

0.57

0.004

0.001

0.001

0.02

WHOQOL-BREF: Environmental

 Sham

56.0 (44.0–69)

56.0 (47.0–69.0)

56.0 (44.0–72.0)

56.0 (44.0–69.0)

56.0 (44.0–69.0)

 Real

69.0 (56.0–69.0)

56.0 (53.0–75.0)

56.0 (53.0–69.0)

49.0 (56.0–72.0)

56.0 (48.5–69.0)

 p*

0.06

0.28

0.91

0.28

0.94

  1. Sham (n = 41) and Real (n = 45); Data is presented as Median (25Q-75Q); MPQ: McGill Pain Questionnaire; WHOQOL-BREF: WHO-Quality of Life questionnaire.; Asterisk (*) symbol indicates p value between Sham-rTMS and Real-rTMS group. Hash (#) symbol indicates p value within group. *p or #p < 0.05; **p or ##p < 0.01; ***p or ###p < 0.001.
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Advances in Rheumatology

ISSN: 2523-3106