Skip to main content

Table 1 Levels of inflammatory mediators following injection of a galactomannan (GM) or Hylan G-F20 (HY) into mouse joints

From: Hylan G-F20 and galactomannan joint flares are associated to acute synovitis and release of inflammatory cytokines

GroupIL-1βIL-6CXCL-1
Control16.30 + 1.69425.39 + 11.5623.88 + 1.125
HY47.57 + 12.60*542.9 + 303.4*144.0 + 33.35*
GM11.43 + 4.154617.9 + 262.6*288.0 + 58.65*
  1. Mice received GM, HY or saline into the knee. Interleukin (IL)-1, IL-6 and CXCL-1 (pg/mL) levels were measured in joint washings after 6 h. Data are mean ± SD of n = 6/group; *p < 0.05 using one-way ANOVA followed by Tukey’s test