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Table 1 Levels of inflammatory mediators following injection of a galactomannan (GM) or Hylan G-F20 (HY) into mouse joints

From: Hylan G-F20 and galactomannan joint flares are associated to acute synovitis and release of inflammatory cytokines

Group

IL-1β

IL-6

CXCL-1

Control

16.30 + 1.694

25.39 + 11.56

23.88 + 1.125

HY

47.57 + 12.60*

542.9 + 303.4*

144.0 + 33.35*

GM

11.43 + 4.154

617.9 + 262.6*

288.0 + 58.65*

  1. Mice received GM, HY or saline into the knee. Interleukin (IL)-1, IL-6 and CXCL-1 (pg/mL) levels were measured in joint washings after 6 h. Data are mean ± SD of n = 6/group; *p < 0.05 using one-way ANOVA followed by Tukey’s test
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Advances in Rheumatology

ISSN: 2523-3106