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Table 4 Rheumatic manifestations in A143T and R118C subjects

From: Higher rate of rheumatic manifestations and delay in diagnosis in Brazilian Fabry disease patients

Signs/Symptoms/DiagnosisTotal
N (%)
Males
N (%)
Females
N (%)
p-valueA143T
N (%)
R118C
N (%)
p-value
Pain in the extremities (nociceptive and/or neuropathic)10 (52.6%)4 (50%)6 (54.5%)0.862 (50%)8 (53.3%)0.34
Fabry-like crises (past/present)4 (21.1%)04 (36.4%)0.063 (75%)1 (6.7%)0.001
Osteopenia/osteoporosis/ low bone mineral density for age11 (57.9%)5 (62.5%)6 (54.5%)0.753 (75%)8 (53.3%)0.46
Fibromyalgia7 (36.8%)1 (12.5%)6 (54.5%)0.073 (75%)4 (26.7%)0.08
Chronic low back pain3 (15.8%)1 (12.5%)2 (18.2%)0.382 (50%)1 (6.7%)0.04
Hip/knee osteoarthritis3 (15.8%)2 (25%)1 (9.1%)0.3803 (20%)0.36
Trigger finger1 (5.3%)1 (12.5%)001 (6.7%)
Cramps1 (5.3%)1 (12.5%)001 (6.7%)
  1. Data in bold means that the difference of frequencies between males and females was statistically significant