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Table 1 General features of patients with dermatomyositis and antisynthetase syndrome at disease onset

From: The aerobic capacity in patients with antisynthetase syndrome and dermatomyositis

 DM
(n = 13)
ASS
(n = 9)
P
Age at disease diagnosis (years)40.2 ± 11.540.2 ± 10.20.999
Clinical manifestations (%)
 Constitutional symptoms8 (61.5)8 (88.9)0.333
Skin involvement
 Heliotrope rash12 (92.3)0
 Gottron’s sign12 (92.3)0
 Gottron’s papule12 (92.3)0
  “Mechanic’s hands”06 (66.7)
 Joint involvement2 (15.4)8 (88.9)0.001
 Pulmonary involvement4 (30.8)9 (100.0)0.001
 Raynaud’s phenomenon6 (46.2)8 (88.9)0.165
 Dysphagia8 (61.5)3 (33.3)0.193
Muscle involvement (%)
Upper limbs (muscle strength)
 Degree II000.689
 Degree II00
 Degree III2 (15.8)2 (22.2)
 Degree IV11 (84.2)6 (66.7)
 Degree V01 (11.1)
Lower limbs (muscle strength)
 Degree II000.973
 Degree II00
 Degree III3 (23.1)2 (22.2)
 Degree IV9 (69.2)6 (66.7)
 Degree V1 (7.7)1 (11.1)
Laboratory parameters
 Creatine phosphokinase (U/L)2300 (999–6326)967 (292–6654)0.366
Antisynthetase autoantibodies (%)
 Anti- Jo-108 (88.9)
 Anti-PL-1201 (11.1)
  1. ASS antisynthetase syndrome, DM dermatomyositis