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Table 1 Baseline characteristics and reproductive history

From: Baseline characteristics of postmenopausal women with osteoporosis treated with teriparatide in a real-world setting in Latin America: a subregional analysis from the Asia and Latin America Fracture Observational Study (ALAFOS)

CharacteristicColombia
(N = 277)
Brazil
(N = 130)
Mexico
(N = 83)
Argentina
(N = 56)
All Patients Latin America Subregion
(N = 546)
Age (years), mean (SD)72.7 (9.8)68.6 (10.0)67.8 (11.0)72.4 (8.4)71.0 (10.1)
Body mass index (kg/m2), mean (SD)25.1 (3.7)24.8 (4.5)25.6 (3.4)25.3 (4.0)25.2 (3.9)
Bone mineral density (T-score), mean (SD)
Lumbar spine−3.10 (1.11) (n = 185)− 3.30 (1.21) (n = 105)−2.46 (1.28) (n = 73)−2.93 (1.40) (n = 50)−3.02 (1.23) (n = 413)
Total hip−2.45 (1.05) (n = 50)−1.80 (0.86) (n = 64)−2.40 (0.68) (n = 58)− 2.36 (1.23) (n = 27)−2.21 (0.96) (n = 199)
Femoral neck−2.40 (0.95) (n = 137)−1.96 (0.96) (n = 74)−2.35 (0.86) (n = 28)− 2.58 (0.90) (n = 39)−2.31 (0.96) (n = 278)
Patients older than 40 years with ≥1 previous low trauma fracture, n (%)187 (67.5%)67 (51.5%)46 (55.4%)43 (76.8%)343 (62.8%)
Patients older than 40 years with previous low trauma fracture (by number of fractures), n (%)
No fractures90 (32.6%)63 (48.8%)37 (45.1%)13 (23.2%)203 (37.4%)
1 fracture105 (38.0%)39 (30.2%)36 (43.9%)13 (23.2%)193 (35.5%)
2 fractures55 (19.9%)15 (11.6%)8 (9.8%)13 (23.2%)91 (16.8%)
3 fractures13 (4.7%)9 (7.0%)1 (1.2%)9 (16.1%)32 (5.9%)
4 fractures7 (2.5%)1 (0.8%)0 (0.0%)1 (1.8%)9 (1.7%)
5 or more fractures6 (2.2%)2 (1.6%)0 (0.0%)7 (12.5%)15 (2.8%)
Previous fracture sites, n (%)
Vertebral96 (34.7%)28 (21.5%)7 (8.4%)35 (62.5%)166 (30.4%)
Non-vertebral90 (32.5%)28 (21.5%)38 (45.8%)20 (35.7%)176 (32.2%)
Main non-vertebrala70 (25.3%)18 (13.8%)26 (31.3%)14 (25.0%)128 (23.4%)
Hip23 (8.3%)8 (6.2%)1 (1.2%)4 (7.1%)36 (6.6%)
Reproductive history
Age at onset of menopause (years), mean (SD)48.7 (5.2)45.9 (6.6)46.6 (4.9)47.2 (5.0)47.5 (5.6)
Number of fertile yearsb, median (Q1, Q3), years36.0 (32, 38)33.5 (28, 37)36.0 (33, 38)35.0 (32, 39)35.0 (31, 38)
Parityc, n (%) patients
044 (15.9%)15 (11.5%)7 (8.4%)11 (19.6%)77 (14.1%)
129 (10.5%)7 (5.4%)8 (9.6%)10 (17.9%)54 (9.9%)
245 (16.3%)31 (23.8%)20 (24.1%)17 (30.4%)113 (20.7%)
356 (20.3%)23 (17.7%)23 (27.7%)11 (19.6%)113 (20.7%)
434 (12.3%)18 (13.8%)9 (10.8%)5 (8.9%)66 (12.1%)
5 or more68 (24.6%)36 (27.7%)16 (19.3%)2 (3.6%)122 (22.4%)
Early menopause (< age 40), n (%)12 (4.3%)18 (13.8%)5 (6.0%)5 (8.9%)40 (7.3%)
Surgical menopause, n (%)46 (17.8%)17 (13.5%)35 (42.2%)8 (14.5%)106 (20.3%)
  1. N = total number of patients available; n = number of patients with valid (non-missing or unknown) values; SD = standard deviation; Q1 = first quartile; Q3 = third quartile
  2. aRadius, hip, humerus, tibia, pelvis and clavicle
  3. bAge at menopause - age at menstruation
  4. cNumber of times given birth
  5. Note: Percentages are calculated using n, the number of valid (not missing or unknown) responses for each item