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Table 3 Studies comprising measurements on gray-scalea

From: The use of ultrasonography in the diagnosis of nail disease among patients with psoriasis and psoriatic arthritis: a systematic review

Studies Population Gray-scale Result
Arbault et al. (2017) [26] PsA Nail bed thickness
Mean (SD): 0.5 mm (0.04)
Nail plate thickness
Mean (SD): 2.0 mm (0.42)
Fassio et al. (2017) [28] PsO Nail bed thickness
Mean (SD): 0.25 mm (0.05)
Nail plate thickness
Mean (SD): 0.063 mm (0.011)
Healthy controls had lower nail plate and nail bed thickness.
PsA Nail bed thickness
Mean (SD): 0.25 mm (0.04)
Nail plate thickness
Mean (SD): 0.065 mm (0.014)
Controls Nail bed thickness
Mean (SD): 0.22 mm (0.02)
Nail plate thickness
Mean (SD): 0.051 mm (0.006)
Acquitter et al. (2016) [30] Patients with PsO with nail disease Nail matrix thickness
Median (SD): 1.94 mm (0.69)
Patients with PsO with nail disease presented with significantly higher nail matrix thickness than patients with scalp PsO and/or inverse PsO (p < 0.01).
Patients with scalp PsO and/or inverse PsO Nail matrix thickness
Median (SD): 1.77 mm (0.54)
Marina et al. (2016) [31] PsO Nail bed thickness
Median (IQR): 1.88 mm
(1.71–2.03)
Nail plate thickness
Median (IQR): 0.86 mm (0.60–1.14)
Healthy controls had a statistically significant lower nail plate thickness than patients with PsO (p < 0.0001). No significant differences were observed in nail bed thickness variability among groups (p = 0.4621).
Controls Nail bed thickness
Median (IQR): 1.89 mm (1.78–2.00)
Nail plate thickness
Median (IQR): 0.63 mm (0.59–0.67)
Mendonça et al. (2014) [34] PsA NGS
Mean (SD): 0.48 mm (0.50)
Healthy controls had lower NGS than patients with PsA.
Controls NGS
Mean (SD): 0.00 mm (0.00)
Aydin et al. (2012) [37] PsO Nail thickness
Median (range): 0.56 mm (0.3–1.9)
Healthy controls had slightly lower NGS than patients with PsO.
Controls Nail thickness
Median (range): 0.5 mm
(0.3–0.6)
Gisondi et al. (2012) [38] PsO Nail plate thickness
70 patients (50%)
Haddad et al. (2012) [39] PsO Nail bed thickness
Mean (SD): 16.0 mm (2.9)
Nail matrix thickness
Mean (SD): 17.5 mm (2.9)
Comparing the three groups, patients with PsO and PsA presented with statistically significant higher values of nail bed thickness and nail matrix thickness than controls (p < 0.0001).
Comparing patients with PsO and PsA, patients with PsO presented with a significantly lower nail matrix thickness than patients with PsA (p = 0.002). No statistically significant differences were observed in nail bed thickness among those groups (p = 0.81).
PsA Nail bed thickness
Mean (SD): 15.9 mm (3.0)
Nail matrix thickness
Mean (SD): 18.8 mm (3.0)
Controls Nail bed thickness
Mean (SD): 14.1 mm (1.2)
Nail matrix thickness
Mean (SD): 15.8 mm (0.92)
  1. IQR interquartile range, NGS standard trilaminar appearance of the nail, PD power Doppler, PsA psoriatic arthritis, PsO psoriasis, SD standard deviation
  2. aOnly studies with quantitative results regarding nail thickness, trilaminar appearance, presence of PD signal, and nail resistive index were included in this table