TY - JOUR AU - Azevedo, Valderilio Feijó AU - Kos, Igor Age AU - Vargas-Santos, Ana Beatriz AU - da Rocha Castelar Pinheiro, Geraldo AU - dos Santos Paiva, Eduardo PY - 2019 DA - 2019/08/07 TI - Benzbromarone in the treatment of gout JO - Advances in Rheumatology SP - 37 VL - 59 IS - 1 AB - Benzbromarone is a uricosuric drug that has been used in the treatment of gout over the last 30 years. Due to its potent inhibition of the dominant apical (luminal) urate exchanger in the human proximal tubule URAT1, it reduces the urate reabsorption, diminishing serum urate levels and therefore preventing gout flares. SN - 2523-3106 UR - https://doi.org/10.1186/s42358-019-0080-x DO - 10.1186/s42358-019-0080-x ID - Azevedo2019 ER -