Table 3 Distribution of SLE and controls according to the gene copy number for total C4, C4A and C4B
GCN | C4 n (%) | C4A n (%) | C4B n (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|
Controls (n = 301) | SLE (n = 427) | p-value | Controls (n = 301) | SLE (n = 427) | p-value | Controls (n = 301) | SLE (n = 427) | p-value | |
0 | 0 (0) | 0 (0) | 1.00 | 1 (0.3) | 9 (2.1) | 0.053 | 5 (1.7) | 14 (3.3) | 0.239 |
1 | 0 (0) | 1 (0.2) | 1.00 | 19 (6.3) | 78 (18.3) | < 0.001 | 56 (18.6) | 102 (23.9) | 0.100 |
2 | 3 (1.0) | 30 (7.0) | < 0.001 | 209 (69.4) | 249 (58.3) | < 0.01 | 198 (65.8) | 245 (57.4) | 0.025 |
3 | 38 (12.6) | 94 (22.0) | < 0.01 | 57 (18.9) | 69 (16.2) | 0.371 | 36 (12.0) | 56 (13.1) | 0.734 |
4 | 190 (63.1) | 224 (52.5) | < 0.01 | 9 (3.0) | 16 (3.7) | 0.682 | 3 (1.0) | 9 (2.1) | 0.377 |
5 | 53 (17.6) | 60 (14.1) | 0.213 | 5 (1.7) | 4 (0.9) | 0.500 | 3 (1.0) | 1 (0.2) | 0.312 |
6 | 11 (3.7) | 11 (2.6) | 0.510 | 1 (0.3) | 2 (0.5) | 1.00 | Â | Â | Â |
7 | 4 (1.3) | 6 (1.4) | 1.00 | Â | Â | Â | Â | Â | Â |
8 | 2 (0.7) | 1 (0.2) | 0.573 | Â | Â | Â | Â | Â | Â |