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Fig. 5 | Advances in Rheumatology

Fig. 5

From: CD4+CD69+ T cells and CD4+CD25+FoxP3+ Treg cells imbalance in peripheral blood, spleen and peritoneal lavage from pristane-induced systemic lupus erythematosus (SLE) mice

Fig. 5

Dot-plot and histograms of lymphocytes separated by size and granularity (a and b) and the subpopulation of CD4 T cells (c and d) which expresses CD25 and FoxP3, highlighted in the larger quadrant, of a control (e and f) and a SLE induced animal (g and h). i: Expression of Treg CD4+CD25+FoxP3+ cells in blood (a). spleen (b) and PL (c) from SLE induced animals (dark bars) and controls (light bars) on T90 and T120. The results are expressed by mean ± SD. Mann-Whitney Test. *p<0.005. Scatter plot showing results of Pearson’s correlation analysis. Positive correlation between Treg cells in blood of SLE-induced animals and (j) TNF-α (r=0.379, p<0.043) and (k) TGFβ3 (r=0.342, p=0.038). *p=0.005.

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