Skip to main content

Table 1 Main differences between the Brazilian Consensus for Autoantibodies on HEp-2 cells (BCA) and the International Consensus on Ana Patterns (ICAP)

From: V Brazilian consensus guidelines for detection of anti-cell autoantibodies on hep-2 cells

 BCAICAP
Total patterns3330
Classification groups(5) nuclear, nucleolar, mitotic cytoplasmic, mixed/compound(3) nuclear, mitotic, cytoplasmic
Patterns not recognizedAC-28 mitotic chromosomeBAC-1, BAC-2, BAC-3, BAC-4 and BAC-5#
Nuclear dense fine speckled (AC-2)optional reportcompetent-level
 AC-6 and AC-7reported togetherreported isolated
 AC-9metaphase plate classified as amorphousmetaphase plate classified as positive
 AC-13designated as mandatory reportdesignated as expert-level report
 AC-14mixed/compoundnuclear
 AC-21designated as optional reportdesignated as competent-level
 AC-23designated as optional reportdesignated as competent-level
 AC-24designated as mandatory reportdesignated as expert-level report
 AC-25designated as mandatory reportdesignated as expert-level report
 AC-27designated as mandatory reportdesignated as expert-level report
  1. BCA Brazilian Consensus on Autoantibodies, ICAP International Consensus on Ana Patterns. #BAC-1 nuclear coarse speckled plus nucleolar homogeneous with peripheral staining of metaphase plate, BAC-2 nuclear fine specked and nucleolar speckled plus discrete bright dots at the metaphase plate (NOR), BAC-3 nuclear quasi-homogeneous, BAC-4 nuclear reticular coarse speckled