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Table 1 Main differences between the Brazilian Consensus for Autoantibodies on HEp-2 cells (BCA) and the International Consensus on Ana Patterns (ICAP)

From: V Brazilian consensus guidelines for detection of anti-cell autoantibodies on hep-2 cells

 

BCA

ICAP

Total patterns

33

30

Classification groups

(5) nuclear, nucleolar, mitotic cytoplasmic, mixed/compound

(3) nuclear, mitotic, cytoplasmic

Patterns not recognized

AC-28 mitotic chromosome

BAC-1, BAC-2, BAC-3, BAC-4 and BAC-5#

Nuclear dense fine speckled (AC-2)

optional report

competent-level

 AC-6 and AC-7

reported together

reported isolated

 AC-9

metaphase plate classified as amorphous

metaphase plate classified as positive

 AC-13

designated as mandatory report

designated as expert-level report

 AC-14

mixed/compound

nuclear

 AC-21

designated as optional report

designated as competent-level

 AC-23

designated as optional report

designated as competent-level

 AC-24

designated as mandatory report

designated as expert-level report

 AC-25

designated as mandatory report

designated as expert-level report

 AC-27

designated as mandatory report

designated as expert-level report

  1. BCA Brazilian Consensus on Autoantibodies, ICAP International Consensus on Ana Patterns. #BAC-1 nuclear coarse speckled plus nucleolar homogeneous with peripheral staining of metaphase plate, BAC-2 nuclear fine specked and nucleolar speckled plus discrete bright dots at the metaphase plate (NOR), BAC-3 nuclear quasi-homogeneous, BAC-4 nuclear reticular coarse speckled