Skip to main content

Table 2 Characteristics of the thirteen patients with renal impairment due to Henoch-Schönlein Purpura in use of azathioprine

From: The profile and clinical outcomes of patients with renal involvement due to IgA vasculitis: is azathioprine a good option for treatment?

P

G

Age

GFR

T0 / T1

(ml/min/1.73m2)

Pt max

T0

(mg/kg/day)

Hematuria

Biopsy

1

F

6

60 / 201.6

88

micro

Proliferative glomerulonephritis with segmental crescents. Presence of IgA, C3, kappa and lambda deposits.

2

F

5

99 / 121.2

17.4

Not performed.

3

M

11

135.6 / 162.8

79

macro

Segmental sclerosis in 4/9 glomeruli,mesangial deposits of IgA, C3, kappa and lambda.

4

M

8

132 / NP

148

Not performed - lost to medical follow up.

5

M

10

113.6 / NP

20

Not performed - lost to medical follow up.

6

F

5

126.5 /127.6

144

micro

Slight increase of mesangial cells, with IgA mesangial deposits.

7

M

4

43.21 / 100.8

24

macro

IgA and IgM glomerular deposits and mesangial C3 deposits.

8

M

6

182.7 / 147.9

396

macro

100%crescents andIgA and polyclonal C3 deposits.

9

M

10

104.5/104.5

30

micro

Segmental glomerular sclerosis Glomerular mesangial deposits of IgA.

10

F

6

293.33/ 220

150

macro

Glomerular mesangial deposits of IgA.

11

M

10

112.3 / 94.1

20

micro

Discrete proliferative mesangial glomerulonephritis, with IgA mesangial deposits.

12

F

11

117 / 117.8

261

micro

Focal segmental proliferative necrotizing glomerulonephritis, with 30% crescents, with deposits of IgA, IgM and C3.

13

F

9

126.5 / 108.4

95

micro

Diffuse proliferative mesangial glomerulonephritis, focal necrotizing glomerulitis with fibrocellular crescents and IgA and C3 deposits.

  1. P patient, G gender, Age - in years; GFR: Glomerular Filtration Rate; T0 – initial; T1 – after one year; Pt: proteinuria; M – male; F – female; macro- macroscopic; micro – microscopic