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Table 2 Characteristics of the thirteen patients with renal impairment due to Henoch-Schönlein Purpura in use of azathioprine

From: The profile and clinical outcomes of patients with renal involvement due to IgA vasculitis: is azathioprine a good option for treatment?

P G Age GFR
T0 / T1
(ml/min/1.73m2)
Pt max
T0
(mg/kg/day)
Hematuria Biopsy
1 F 6 60 / 201.6 88 micro Proliferative glomerulonephritis with segmental crescents. Presence of IgA, C3, kappa and lambda deposits.
2 F 5 99 / 121.2 17.4 Not performed.
3 M 11 135.6 / 162.8 79 macro Segmental sclerosis in 4/9 glomeruli,mesangial deposits of IgA, C3, kappa and lambda.
4 M 8 132 / NP 148 Not performed - lost to medical follow up.
5 M 10 113.6 / NP 20 Not performed - lost to medical follow up.
6 F 5 126.5 /127.6 144 micro Slight increase of mesangial cells, with IgA mesangial deposits.
7 M 4 43.21 / 100.8 24 macro IgA and IgM glomerular deposits and mesangial C3 deposits.
8 M 6 182.7 / 147.9 396 macro 100%crescents andIgA and polyclonal C3 deposits.
9 M 10 104.5/104.5 30 micro Segmental glomerular sclerosis Glomerular mesangial deposits of IgA.
10 F 6 293.33/ 220 150 macro Glomerular mesangial deposits of IgA.
11 M 10 112.3 / 94.1 20 micro Discrete proliferative mesangial glomerulonephritis, with IgA mesangial deposits.
12 F 11 117 / 117.8 261 micro Focal segmental proliferative necrotizing glomerulonephritis, with 30% crescents, with deposits of IgA, IgM and C3.
13 F 9 126.5 / 108.4 95 micro Diffuse proliferative mesangial glomerulonephritis, focal necrotizing glomerulitis with fibrocellular crescents and IgA and C3 deposits.
  1. P patient, G gender, Age - in years; GFR: Glomerular Filtration Rate; T0 – initial; T1 – after one year; Pt: proteinuria; M – male; F – female; macro- macroscopic; micro – microscopic