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Table 1 Demographic data and clinical manifestations of the 67 patients with nephritis due to Henoch-Schönlein Purpura

From: The profile and clinical outcomes of patients with renal involvement due to IgA vasculitis: is azathioprine a good option for treatment?

Demographic and clinical data Total number N = 67(%) Patients off immunosuppressants N = 54(%) Patients on immunosuppressants N = 13 (%) p-value
Female 42 (62.6) 36 (66) 6 (46.1) 0.680*
Age at onset (mean age in years, min. - max.) 7 (2–15) 6.5 (2–15) 8.0 (4–11) 0.453***
Time of follow up (median in years, min-max.) 4.0 (1–12) 2 (1–12) 4(1–9) < 0.001***
Cutaneous necrosis or ulcerations 6 (8.9) 5 (9.2) 1 (7.6) 0.190**
Intestinal Impairment 47 (70.1) 37 (68.5) 10 (76.9) 1.0**
Intestinal bleeding 15 (22.3) 13 (24) 2 (15.3) 0.719**
Arthritis 41 (61.1) 32 (59.2) 9 (69.2) 0.604*
Initial renal impairment 53 (79.1) 40 (74) 13 (100)  
Microscopic hematuria 45 (67.1) 41 (75.9) 4 (30.7) 0.349**
Macroscopic hematuria 14 (20.8) 7 (12.9) 7 (5.,8) 0.277**
Isolated hematuria 22 (32.8) 22 (40) 0 0.003**
Isolated proteinuria 6 (8.9) 5 (9.2) 1 (7.6) 0.790**
Non-nephrotic proteinuria 33 (49.2) 29 (5.7) 4 (30.7) 0.206*
Nephrotic proteinuria 10 (14.9) 1 (1.8) 9 (69.2) 0.000**
Nephritic syndrome 6 (8.9) 1 (1.8) 5 (38) 0.001**
Kidney biopsy 20 (29.8) 10 (18.5) 10 (76.9) 0,0002**
Reduction of renal function 1 (1.5) 0 1 (7.6) 0.209**
Systemic Arterial Hypertension 12 (17.9) 5 (9.2) 7 (53.8) 0.001**
Scrotal involvement 0 0 0 0
Pulmonary involvement 0 0 0 0
Neuropsychiatric involvement 0 0 0 0
Pulse therapy with IVglucocorticoid 16 (23.8) 7 (12.9) 9 (69.2) 0.000**
Oral glucocorticoid 40 (59.7) 27 (39.7) 13 (100) 0.045*
  1. SD standard deviation, IV intravenous; *chi-squared test; **Fisher’s test;***Mann-Whitney’s test