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Table 5 Performance measures for ACR 1997, SLICC and new EULAR/ACR criteria, at 1-year-follow-up

From: Comparison among ACR1997, SLICC and the new EULAR/ACR classification criteria in childhood-onset systemic lupus erythematosus

Classification System

Cut-off point

Sensitivity (IC 95%)

Specificity (IC 95%)

PPV (%)

NPV (%)

Cut-off point accuracy (IC 95%)

ACR 1997

≥ 4 criteria

95.1

76.4

84.7

91.9

87.2

(89.6–98.2)

(66.2–84.8)

  

(81.9–91.4)

EULAR/ACR

Total score ≥ 10

95.1

58.4

75.8

89.7

79.6

(89.6–98.2)

(47.5–68.8)

  

(73.6–84.8)

Total score ≥ 13

91.0

83.2

88.1

87.1

87.7

(84.4–95.4)

(73.7–90.3)

  

(82.5–91.8)

SLICC

≥ 4 criteria

97.5

76.4

85.0

95.8

88.6

(93.0–99.5)

(66.2–84.8)

  

(83.6–92.6)

  1. IC 95–95% confidence interval, PPV positive predictive value, NPV negative predictive value, ACR American College of Rheumatology, SLICC Systemic Lupus International Collaborating Clinics criteria, EULAR/ACR European League Against Rheumatism (EULAR)/ACR