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Table 4 Performance measures for ACR 1997, SLICC and new EULAR/ACR criteria, at baseline/first visit

From: Comparison among ACR1997, SLICC and the new EULAR/ACR classification criteria in childhood-onset systemic lupus erythematosus

Classification System Cut-off point Sensitivity (IC 95%) Specificity (IC 95%) PPV (%) NPV (%) Cut-off point accuracy (IC 95%)
ACR 1997 ≥ 4 70.5% 83.2% 85.2% 67.3% 75.8
criteria (61.6–78.4) (73.7–90.3)    (69.5–81.4)
EULAR/ACR Total 87.7 67.4 78.7 80.0 79.2
score ≥ 10 (80.5–93.0) (56.7–77.0)    (73.0–84.4)
Total 76.2 87.6 89.4 72.9 81.0
score ≥ 13 (67.9–83.5) (79.0–93.7)    (75.1–86.1)
SLICC ≥ 4 89.3 80.9 86.5 84.7 85.8
criteria (82.5–94.2) (71.2–88.5)    (80.3–90.2)
  1. IC 95–95% confidence interval, PPV positive predictive value, NPV negative predictive value, ACR American College of Rheumatology, SLICC Systemic Lupus International Collaborating Clinics criteria, EULAR/ACR European League Against Rheumatism (EULAR)/ACR