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Table 1 Clinical and laboratory data of 22 patients with autoimmune rheumatic disease (AIRD) and positive cytomegalovirus antigenemia

From: Incidence of Cytomegalovirus Antigenemia in patients with autoimmune rheumatic diseases: a 3-year retrospective study

Patient Age (years)/ Sex AIRD Immunosuppressive therapy in hospital Lymphocyte Count (/μl) Positive CMV antigenemia nuclei (/200.000PMN) Sites involved by CMV infection Symptoms Outcome
1 67/F SLE CFA, PDN 130 mg/day 1311 32 Gut Esophageal ulcers Death
2 34/F SLE AZA, CFA, PDN 80 mg/day 1356 1 Lung Cough, dyspnea, fever Improvement
3 17/F SLE PDN 200 mg/day 444 2 Cytopenia Neutropenia, Thrombocytopenia Improvement
4 22/F SLE PDN 60 mg/day 695 5 Gut Mouth ulcers Improvement
5 21/F SLE PDN 60 mg/day 135 500 Cytopenia / Lung Trombocyotpenia, Cough, dyspnea, fever Death
6 25/F SLE PDN 180 mg/day 525 1 Lung Cough, dyspnea, fever Death
7 16/F SLE MP + CFA, PDN 50 mg/day 850 108 Cytopenia Febrile neutropenia Improvement
8 20/F SLE MP + CFA, PDN 60 mg/day 792 1 Gut Esophageal ulcers Improvement
9 38/F SLE PDN 60 mg/day 2751 2 Lung Cough, dyspnea, fever Improvement
10 30/F SLE CFA, PDN 60 mg/day 659 2 Cytopenia Pancytopenia, fever Death
11 25/F SLE MMF, MP, PDN 50 mg/day 853 164 Cytopenia Anemia, Thrombocytopenia Improvement
12 37/F SLE PDN 60 mg/day 80 46 Cytopenia /Gut Anemia, diarrhea Improvement
13 26/F SLE MP + CFA, PDN 90 mg/day 714 2 Lung Cough, dyspnea Improvement
14 77/F SE 125 1 Cytopenia Pancytopenia, fever Death
15 29/M Overlap Sd. PDN160mg/day 246 16 Lung Cough, dyspnea Death
16 70/M RA MP, PDN 20 mg/day 77 1 Cytopenia Pancytopenia, fever Improvement
17 17/M RA PDN 160 mg/day 689 1 Lung Cough, dyspnea Death
18 42/F MPA PDN 100 mg/day 197 4 Lung Cough, dyspnea, Fever Death
19 77/F MPA PDN 100 mg/day 372 500 Cytopenia / Lung Anemia, Leukopenia, Cough, Fever Death
20 63/F GPA CFA, PDN 30 mg/day 857 9 Gut Gastric ulcer Improvement
21 58/M GPA AZA, MP, PDN 120 mg/day 213 73 Gut Gastric ulcer Death
22 55/F Anti-sintetase Sd. CFA, PDN 100 mg/day 975 7 Lung Cough, dyspnea Improvement
  1. CMV cytomegalovirus, SLE Systemic Lupus Erythematosus, SE Systemic sclerosis, Overlap syndrome Systemic Lupus Erythematosus + Systemic sclerosis + polymyositis, RA rheumatoid arthritis, MPA microscopic polyangiitis, GPA granulomatosis with polyangiitis, F Female, M, Male, AIRD autoimmune rheumatic disease, PDN Prednisone, AZA Azathioprine, MMF mycophenolate mofetil, CFA Cyclophosphamide (pulse), MP Methylprednisolone (pulse), MP + CFA combined pulse: methylprednisolone and cyclophosphamide. a: Maximum dose during hospitalization. b: methylprednisolone pulse 1 g / day for 3 consecutive days