Table 1 Clinical and laboratory data of 22 patients with autoimmune rheumatic disease (AIRD) and positive cytomegalovirus antigenemia
Patient | Age (years)/ Sex | AIRD | Immunosuppressive therapy in hospital | Lymphocyte Count (/μl) | Positive CMV antigenemia nuclei (/200.000PMN) | Sites involved by CMV infection | Symptoms | Outcome |
|---|---|---|---|---|---|---|---|---|
1 | 67/F | SLE | CFA, PDN 130 mg/day | 1311 | 32 | Gut | Esophageal ulcers | Death |
2 | 34/F | SLE | AZA, CFA, PDN 80 mg/day | 1356 | 1 | Lung | Cough, dyspnea, fever | Improvement |
3 | 17/F | SLE | PDN 200 mg/day | 444 | 2 | Cytopenia | Neutropenia, Thrombocytopenia | Improvement |
4 | 22/F | SLE | PDN 60 mg/day | 695 | 5 | Gut | Mouth ulcers | Improvement |
5 | 21/F | SLE | PDN 60 mg/day | 135 | 500 | Cytopenia / Lung | Trombocyotpenia, Cough, dyspnea, fever | Death |
6 | 25/F | SLE | PDN 180 mg/day | 525 | 1 | Lung | Cough, dyspnea, fever | Death |
7 | 16/F | SLE | MP + CFA, PDN 50 mg/day | 850 | 108 | Cytopenia | Febrile neutropenia | Improvement |
8 | 20/F | SLE | MP + CFA, PDN 60 mg/day | 792 | 1 | Gut | Esophageal ulcers | Improvement |
9 | 38/F | SLE | PDN 60 mg/day | 2751 | 2 | Lung | Cough, dyspnea, fever | Improvement |
10 | 30/F | SLE | CFA, PDN 60 mg/day | 659 | 2 | Cytopenia | Pancytopenia, fever | Death |
11 | 25/F | SLE | MMF, MP, PDN 50 mg/day | 853 | 164 | Cytopenia | Anemia, Thrombocytopenia | Improvement |
12 | 37/F | SLE | PDN 60 mg/day | 80 | 46 | Cytopenia /Gut | Anemia, diarrhea | Improvement |
13 | 26/F | SLE | MP + CFA, PDN 90 mg/day | 714 | 2 | Lung | Cough, dyspnea | Improvement |
14 | 77/F | SE | – | 125 | 1 | Cytopenia | Pancytopenia, fever | Death |
15 | 29/M | Overlap Sd. | PDN160mg/day | 246 | 16 | Lung | Cough, dyspnea | Death |
16 | 70/M | RA | MP, PDN 20 mg/day | 77 | 1 | Cytopenia | Pancytopenia, fever | Improvement |
17 | 17/M | RA | PDN 160 mg/day | 689 | 1 | Lung | Cough, dyspnea | Death |
18 | 42/F | MPA | PDN 100 mg/day | 197 | 4 | Lung | Cough, dyspnea, Fever | Death |
19 | 77/F | MPA | PDN 100 mg/day | 372 | 500 | Cytopenia / Lung | Anemia, Leukopenia, Cough, Fever | Death |
20 | 63/F | GPA | CFA, PDN 30 mg/day | 857 | 9 | Gut | Gastric ulcer | Improvement |
21 | 58/M | GPA | AZA, MP, PDN 120 mg/day | 213 | 73 | Gut | Gastric ulcer | Death |
22 | 55/F | Anti-sintetase Sd. | CFA, PDN 100 mg/day | 975 | 7 | Lung | Cough, dyspnea | Improvement |