Table 4 Relationship between anti-C1q antibody and other disease parameters among patients under study
Variable n (%) or meanāĀ±āSD | Positive Anti-C1q (nā=ā34) | Negative Anti-C1q (nā=ā46) | t/x2 | P value | |
|---|---|---|---|---|---|
Clinical features | Arthritis | 31 (91.2) | 41 (89.1) | 0.091 | 0.763 |
Pleurisy | 15 (35.7) | 27 (58.7) | 1.666 | 0.197 | |
Fever | 19 (55.9) | 20 (43.5) | 1.204 | 0.273 | |
Malar rash | 20 (58.8) | 30 (65.2) | 0.341 | 0.559 | |
Oral ulcers | 17 (50.0) | 21 (45.7) | 0.148 | 0.700 | |
Alopecia | 13 (38.2) | 21 (61.8) | 0.440 | 0.507 | |
Photosensitivity | 11 (32.4) | 20 (43.5) | 1.020 | 0.313 | |
Neurologic manifestations | 6 (17.6) | 14 (30.4) | 1.705 | 0.192 | |
APS | 6 (17.6) | 13 (28.3) | 1.216 | 0.270 | |
Vasculitis | 10 (29.4) | 4 (8.7) | 5.811 | 0.016 | |
Pericarditis | 5 (14.7) | 5 (10.9) | 0.263 | 0.608 | |
Discoid rash | 4 (11.8) | 2 (4.3) | 1.550 | 0.213 | |
Myositis | 0 (0.0) | 1 (2.2) | 0.748 | 0.387 | |
Nephritis | 23 (67.6) | 17 (37.0) | 7.366 | 0.007 | |
ECLAM | Ā | 4.2āĀ±ā1.9 | 3.5āĀ±ā2.2 | 1.572 | 0.120 |
Laboratory features | ESR (mm/1st hour) | 57.7āĀ±ā32.5 | 41.1āĀ±ā26.8 | 2.500 | 0.015 |
Serum creatinine (Ī¼mol/L) | 0.9āĀ±ā0.7 | 0.8āĀ±ā0.3 | 0.643 | 0.500 | |
Serum albumin (g/dl) | 3.6āĀ±ā0.5 | 4.0āĀ±ā0.8 | 2.677 | 0.009 | |
Low C3ā<ā90 (mg/dl) | 20 (58.8) | 16 (34.8) | 4.565 | 0.033 | |
Low C4ā<ā10 (mg/dl) | 12 (35.3) | 7 (15.2) | 4.351 | 0.037 | |