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Table 2 Demographic data, cumulative clinical manifestations and laboratory parameters, and SLEDAI-2 K in childhood-onset systemic lupus erythematosous (cSLE) patients with lupus erythematosus panniculitis (LEP)

From: Panniculitis in childhood-onset systemic lupus erythematosus: a multicentric cohort study

Variables cSLE with LEP (at diagnosis) (n = 6) cSLE without LEP (at last visit) (n = 60) P
Demographic data
 Age at diagnosis, years 15 (10–21) 15 (2–25) 0.624
 Female gender 4 (67) 52 (87) 0.222
 Disease duration, years 2.75 (0–11.4) 2.83 (0–11.8) 0.297
Cumulative clinical manifestations
 Constitutional involvement 4 (67) 6 (10) 0.003
 Cutaneous vasculitis 3 (50) 6 (10) 0.029
 Musculoskeletal involvement 3 (50) 4 (7) 0.013
 Serositis 0 (0) 4 (7) 1.000
 Neuropsychiatric involvement 0 (0) 8 (13) 1.000
 Nephritis 1 (17) 19/59 (32) 0.657
Cumulative laboratory parameters
 Leukopenia, <  4000/mm3 4 (67) 4/55 (7) 0.002
 Anti-ds-DNA 4 (67) 17/47 (36) 0.200
Disease activity at diagnosis
 SLEDAI-2 K 9 (0–25) 4 (0–41) 0.352
  1. * P - value according to Bonferroni correction for multiple comparisons (p < 0.004). Results are presented in n (%) and median (range), SLEDAI-2 K - Systemic Lupus Erythematosus Disease Activity Index 2000