Table 2 Demographic data, cumulative clinical manifestations and laboratory parameters, and SLEDAI-2 K in childhood-onset systemic lupus erythematosous (cSLE) patients with lupus erythematosus panniculitis (LEP)
From: Panniculitis in childhood-onset systemic lupus erythematosus: a multicentric cohort study
Variables | cSLE with LEP (at diagnosis) (n = 6) | cSLE without LEP (at last visit) (n = 60) | P |
|---|---|---|---|
Demographic data | |||
Age at diagnosis, years | 15 (10–21) | 15 (2–25) | 0.624 |
Female gender | 4 (67) | 52 (87) | 0.222 |
Disease duration, years | 2.75 (0–11.4) | 2.83 (0–11.8) | 0.297 |
Cumulative clinical manifestations | |||
Constitutional involvement | 4 (67) | 6 (10) | 0.003 |
Cutaneous vasculitis | 3 (50) | 6 (10) | 0.029 |
Musculoskeletal involvement | 3 (50) | 4 (7) | 0.013 |
Serositis | 0 (0) | 4 (7) | 1.000 |
Neuropsychiatric involvement | 0 (0) | 8 (13) | 1.000 |
Nephritis | 1 (17) | 19/59 (32) | 0.657 |
Cumulative laboratory parameters | |||
Leukopenia, < 4000/mm3 | 4 (67) | 4/55 (7) | 0.002 |
Anti-ds-DNA | 4 (67) | 17/47 (36) | 0.200 |
Disease activity at diagnosis | |||
SLEDAI-2 K | 9 (0–25) | 4 (0–41) | 0.352 |