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Table 1 Baseline clinical and demographic characteristics in ITT population (N = 89)

From: Multicenter, randomized, double-blind clinical trial to evaluate efficacy and safety of combined glucosamine sulfate and chondroitin sulfate capsules for treating knee osteoarthritis

Characteristic Glucosamine sulfate and chondroitin sulfate group (n = 45) Cosamin DS® Group (n = 44) p value
Age (years), mean ± SD 63.4 ± 8.3 64 ± 10.2 0.753
Female, N (%) 43 (95.6) 40 (90.9) 0.434
Color, white, N (%) 30 (66.7) 28 (63.6) 0.584
OA diagnosis time (years), mean ± SD 4.20 (± 4.25) 5.20 (± 7.0) 0.734
BMI (kg/m2), mean ± SD 26.5 ± 2.4 26.7 ± 2.9 0.440
Kellgren and Lawrence classification, N (%)
 Grade I 7 (15.6) 7 (15.9) 0.224
 Grade II 24 (53.3) 16 (36.4)  
 Grade III 14 (31.1) 21 (47.7)  
OA family history, N (%) 12 (26.7) 12 (27.3) 0.949
Pain intensity, cm (VAS; 0-10 cm) 6.72 (± 1.61) 6.36 (± 1.45) 0.313
Evaluation of joint pain, N (%)
 No pain 1 (2.2%) 3 (6.8%) 0.361
 Subject reports pain 22 (48.9%) 19 (43.2%) 0.672
 Subject reports pain and changes facial expression 20 (44.4%) 20 (45.5%) > 0.999
 Subject reports pain, changes facial expression and makes moves to cut limb 2 (4.4%) 2 (4.5%) > 0.999
Lequesne Index (0–24), mean ± SD 8.57 (± 2.2) 8.58 (± 2.47) 0.931
Swelling, N (%)
 Absent 37 (82.2) 36 (81.8) 0.960
 Present 8 (17.8) 8 (18.2)  
  1. SD standard deviation, VAS visual analog scale, BMI body mass index, ITT intention to treat, OA osteoarthritis