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Table 1 Demographic, clinical and laboratory features of adult and juvenile dermatomyositis

From: Comparison between treatment naive juvenile and adult dermatomyositis muscle biopsies: difference of inflammatory cells phenotyping

Features Adult DM
(N = 28)
Juvenile DM
(N = 28)
P value
Age at disease onset (years) 42.0 ± 15.9 7.3 ± 3.4  
 Disease duration (months) 7.0 [3.3–12.0] 4.0 [2.0–16.5] 0.274
 Gender: female 24 (85.7) 20 (71.4) 0.329
Cutaneous involvement
 Heliotrope rash 26 (92.9) 21 (75.0) 0.243
 Gottron’s papules 28 (100.0) 22 (78.6) 0.481
Muscle strength
 Upper limbs (Degree: 0-V) IV [IV-IV] III [III-IV] < 0.001
 Lower limbs (Degree: 0-V) III [III-IV] III [III-IV] 0.652
Articular involvement 11 (39.3) 8 (28.6) 0.577
Pulmonary involvement 7 (25.0) 3 (10.7) 0.295
Laboratory alterations
 Creatine phosphokinase (U/L) 640 [144–8069] 556 [155–1659] 0.407
 Aldolase (U/L) 14 [8–60] 16 [14–24] 0.783
  1. Data expressed as mean ± standard deviation, median [interquartile 25th - 75th] or percentage (%)
  2. DM dermatomyositis