Table 1 Demographic, clinical and laboratory features of adult and juvenile dermatomyositis
Features | Adult DM (N = 28) | Juvenile DM (N = 28) | P value |
|---|---|---|---|
Age at disease onset (years) | 42.0 ± 15.9 | 7.3 ± 3.4 | |
Disease duration (months) | 7.0 [3.3–12.0] | 4.0 [2.0–16.5] | 0.274 |
Gender: female | 24 (85.7) | 20 (71.4) | 0.329 |
Cutaneous involvement | |||
Heliotrope rash | 26 (92.9) | 21 (75.0) | 0.243 |
Gottron’s papules | 28 (100.0) | 22 (78.6) | 0.481 |
Muscle strength | |||
Upper limbs (Degree: 0-V) | IV [IV-IV] | III [III-IV] | < 0.001 |
Lower limbs (Degree: 0-V) | III [III-IV] | III [III-IV] | 0.652 |
Articular involvement | 11 (39.3) | 8 (28.6) | 0.577 |
Pulmonary involvement | 7 (25.0) | 3 (10.7) | 0.295 |
Laboratory alterations | |||
Creatine phosphokinase (U/L) | 640 [144–8069] | 556 [155–1659] | 0.407 |
Aldolase (U/L) | 14 [8–60] | 16 [14–24] | 0.783 |