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Table 3 Crude and adjusted regression analysis of diagnostic time up to 12 months and independent variables in patients with rheumatoid arthritis in Blumenau, Santa Catarina, Brazil, 2014

From: Prevalence and factors associated with diagnosis of early rheumatoid arthritis in the south of Brazil

Variables Crude analysis Adjusted analysis  
(RPc) CI 95% p (PRa) CI 95% p
Sex (n = 296) 0,704*    0,720**
 Male 1,08 (0,7-1,6)   1,07 (0,7-1,6)  
 Female 1    1   
Age in years (n = 287)    0,894*    0,920**
 20–39 1    1   
 40–59 0,91 (0,4-1,7)   0,91 (0,6-1,7)  
  ≥ 60 0,96 (0,4-1,8)   0,95 (0,4-1,8)  
Education in completed years (n = 284) 0,094    0,041
 0–4 1,37 (0,9-2,1)   1,59 (1,1 - 2, 5)  
 5–8 1,20 (0,7-1,8)   1,29 (0,7-2,1)  
  > 9 1    1   
Current monthly personal income in minimum wages (n = 248) 0,496*    0,741**
 Third tertile (higher) 1    1   
 Second tertile 0,96 (0,6-1,4)   0,91 (0,5-1,4)  
 First tertile (lower) 1,11 (0,7-1,6)   1,07 (0,7-1,6)  
Body mass index (Kg/m2) (n = 285) 0,001    0,001
  ≤ 24,9 1    1   
 25–29,9 1,55 (1,0-2,3)   1,62 (1,0-2,4)  
  ≥ 30 1,97 (1,2-2,9)   2,07 (1, 3 - 3,1)  
Type of servicee in the last 12 months (n = 269) 0,515*    0,997**
 Public healthcare system 0,86 (0,5-1,3)   1,01 (0,6-1,6)  
 Supplementary healthcare system 0,97 (0,6-1,4)   0,90 (0,5-1,4)  
 Fee-for-service care 1    1   
Total number of consultations with a rheumatologist in the last 12 months (n = 281) 0,074    0,223**
 0–1 0,75 (0,4-1,2)   0,79 (0,4-1,3)  
 2–3 1    1   
  ≥ 4 0,72 (0,5-1,0)   0,79 (0,5-1,1)  
Disease time in months (n = 235) 0,134    0,115**
 0–24 1    1   
  > 24 1,57 (0,8-2,8)   1,76 (0,8-3,5)  
Use of csDMARD (n = 296) 0,994*    0,744**
 Yes 1    1   
 No 0,99 (0,7-1,3)   1,08 (0,6-1,7)  
Use of TNFi (ADA + ETA+IFX) (n = 288) 0,588*    0,217**
 Yes 0,91 (0,6-1,2)   0,75 (0,4-1,1)  
 No 1    1   
HAQ (n = 165) 0,227*    0,867**
 0–1 (mild) 1    1   
 1,1–2 (moderate) 0,68 (0,4-1,1)   0,78 (0,6-1,1)  
 2,1–3 (severe) 0,76 (0,4-1,2)   0,82 (0,6-1,3)  
Presence of radiological changes (erosions) in hands (n = 237) 0,668*    0,877**
 No 1    1   
 Yes 1,08 (0,7-1,5)   1,03 (0,6-1,6)  
Current professional situation (237) 0,125    0,088**
 Working 1    1   
 Health insurance 1,11 (0,6-1,8)   1,34 (0,8 – 2,1)  
 Disability retirement 0,99 (0,6-1,4)   0,85 (0,5 – 1,3)  
 Retirement for time of service 0,67 (0,4-1,1)   0,68 (0,4 – 1,1)  
  1. csDMARD conventional synthetic disease-modifying antirheumatic drugs, TNFi tumor necrosis factor inhibitors, ADA adalimumab, ETA etanercept, IFX infliximab, HAQ health assessment questionnaire, PRc crude prevalence ratio; PRa: adjusted prevalence ratio; CI 95%: confidence interval of 95%
  2. * Value of p > 0,20 excluded from the adjusted analysis. ** Value of p > 0,05 excluded of final model