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Table 3 Spearman’s correlation between angiogenic cytokines and diferent disease parameters

From: Relevance of serum angiogenic cytokines in adult patients with dermatomyositis

  ANG ANGPT-1 FGF-1 FGF-2 VEGF PDGF-AA PDGF-BB
rho P rho P rho P rho P rho P rho P rho P
Current age    0.289 0.018        0.399 0.018   
Age at disease onset    0.401 0.005 0.295 0.042      0.416 0.003   
Disease duration    −0.448 0.001 −0.394 0.006      −0.326 0.024 −0.411 0.004
Body mass index          0.317 0.028     
Facial rash 0.387 0.021    0.367 0.010         
“V-neck” sign      0.338 0.019         
“Shawl” sign    0.355 0.013 0.343 0.017         
Pulmonary involvement 0.435 0.009             
Patient VAS 0.410 0.014 0.326 0.024 0.351 0.014 −0.364 0.012       
Physician VAS 0.476 0.004 0.387 0.007 0.341 0.018 −0.385 0.007    0.324 0.025   
MMT-8    −0.470 0.001    −0.413 0.004    −0.457 0.001 −0.382 0.008
HAQ    0.400 0.005        0.338 0.019   
Creatine phosphokinase    0.315 0.035           
Aldolase    0.537 < 0.001 0.397 0.009 −0.344 0.028    0.469 0.002 0.478 0.002
Lactic dehydrogenase      0.339 0.023         
Aspartate aminotransferase      0.429 0.004 −0.398 0.008    0.363 0.016 0.324 0.034
Alanine aminotransferase      0.379 0.010         
Cyclosporin    −0.309 0.032           
Prednisone (current use)    0.463 0.001 0.342 0.017      0.478 0.001 0.510 < 0.001
Prednisone (cumulativea)    −0.390 0.006 −0.399 0.005 0.301 0.040    −0.315 0.029   
ANG 1.000   0.366 0.001 0.512 < 0.001 −0.594 < 0.001    0.408 0.004   
ANGPT-1 0.360 0.034 1.000   0.502 < 0.001 −0.453 0.001    0.820 < 0.001 0.725 < 0.001
FGF-1 0.344 0.034 0.502 < 0.001 1.000   −0.376 0.009    0.437 0.002   
FGF-2    −0.543 0.001 −0.376 0.009 1.000     −0.459 0.001 −0.391 0.007
VEGF          1.000      
PDGF-AA    0.820 < 0.001 0.437 0.002 −0.459 0.001    1.000   0.720 < 0.001
PDGF-BB    0.725 < 0.001    −0.391 0.007    0.720 < 0.001   1.000
  1. ANG angiogenin, ANGPT-1 angiopoietin-1, FGF fibroblast growth factor, HAQ Health Assessment Questionnaire, MMT Muscle Manual Testing, P P value, PDGF platelet-derived growth factor-AA and BB; Rho: Spearmen’s correlation, VAS visual analogue scores, VEGF vascular endothelial growth factor
  2. aSince the disease onset symptoms