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Table 2 Serum levels of angiogenic cytokines in patients with dermatomyositis and healthy individuals

From: Relevance of serum angiogenic cytokines in adult patients with dermatomyositis

Parameters

DM (n = 48)

Control (n = 48)

P value

ANG (ng/mL)

4383 (3588–7251)

3931 (2735–5397)

0.138

ANGPT-1 (ng/mL)

8576 (4964–13,060)

8080 (5785–9609)

0.224

VEGF (ng/mL)

28.6 (5.8–49.3)

38.6 (21.3–72.6)

0.009

FGF-1 (ng/mL)

3.1 (1.8–14.9)

0.7 (0.4–1.8)

< 0.001

FGF-2 (ng/mL)

1.6 (0.6–3.1)

0.3 (0.0–0.9)

< 0.001

PDGF-AA (ng/mL)

545 (304–797)

654 (411–1083)

0.022

PDGF-BB (ng/mL)

2039 (1539–2506)

2107 (1752–2465)

0.358

  1. Results expressed as median (25th - 75th interquartile range)
  2. ANG angiogenin, ANGPT-1 angiopoietin-1, DM dermatomyositis, FGF fibroblast growth factor, PDGF platelet-derived growth factor, VEGF vascular endothelial growth factor