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Table 4 Physical exercise in patients with chronic inclusion body myositis

From: Physical exercise among patients with systemic autoimmune myopathies

Author Patients (n) Protocol (Exercises) Time (week) Evaluated Components Inflammatory markers Results
Spector et al. [35] 5 Strength
Dynamic
12 Isometric strength
3 MVC
↔ CPK
↔ Immune / inflammatory markers
↑ Isometric strength
↑ 3 MVC
↔ Increased cross-sectional area
Arnardottir et al. [39] 7 Strength
Dynamic
12 Isometric strength ↔ CPK
↔ Cytokines
↔ Adhesion molecules
↑ Isometric strength
Johnson et al. [32] 7 Aerobic 12 VO2 peak
Functional Capacity
↔ CPK ↑ VO2 peak
↔ Functional capacity
  7 Strength
Dynamic
16 Muscle strength
Functional capacity
↔ CPK ↑ Muscle strength
↑ Functional capacity
Gualano et al. [36] 1 Strength
Dynamic
With vascular occlusion
12 Muscle strength
Balance
Quality of life
Cross-sectional area
↔ CPK ↑ Muscle strength
↑ Balance
↑ Quality of life
↑ Cross-sectional area
Santos et al. [37] 1 Strength
Dynamic
With vascular occlusion
12 Myostatin gene
Myostatin inhibitor genes
↔ CPK ↓ Myostatin gene
↑ Myostatin inhibitor genes
Jorgensen et al. [38] 1 Strength
Dynamic
With vascular occlusion
12 Isometric strength
Functional capacity
Gait speed
↔ CPK ↑ Isometric strength
↑ Functional capacity
↑ Gait speed
  1. CPK creatine phosphokinase, MVC maximum voluntary contraction, VO 2 peak oxygen consumption, ↑: increase, ↔: no change